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Fgf20

FGF20,全稱(chēng)為成纖維細(xì)胞生長(zhǎng)因子20,常用別名包括FGF-20。它是一類(lèi)參與調(diào)控細(xì)胞生長(zhǎng)、分化與存活的活性蛋白,在機(jī)體多項(xiàng)生理活動(dòng)中發(fā)揮關(guān)鍵作用。在神經(jīng)系統(tǒng)領(lǐng)域,該蛋白對(duì)多巴胺能神經(jīng)元具有顯著的保護(hù)與促生長(zhǎng)效果,這類(lèi)神經(jīng)元的功能異?;驍?shù)量減少,與帕金森病等神經(jīng)退行性疾病的發(fā)生發(fā)展密切相關(guān)。研究發(fā)現(xiàn),F(xiàn)GF20的表達(dá)水平變化可能影響帕金森病的進(jìn)程,因此它成為該疾病治療研究的重要靶點(diǎn)之一。目前,基于FGF20的治療策略正積極推進(jìn),部分靶向該蛋白的生物制劑與基因療法已進(jìn)入臨床試驗(yàn)階段,試圖通過(guò)調(diào)節(jié)其活性或表達(dá)量來(lái)延緩神經(jīng)元損傷,為帕金森病患者提供新的治療希望。

熱銷(xiāo)產(chǎn)品

FGF20 Antibody (CSB-PA059543)

驗(yàn)證數(shù)據(jù)

CSB-PA059543

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA059543(FGF20 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA059543

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA059543(FGF20 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)

Fgf20 Antibodies

Fgf20 for Homo sapiens (Human)

Fgf20 Proteins

Fgf20 Proteins for Rattus norvegicus (Rat)

Fgf20 Proteins for Mus musculus (Mouse)

Fgf20 Proteins for Homo sapiens (Human)

Fgf20 ELISA Kit

Fgf20 ELISA Kit for Homo sapiens (Human)

Fgf20 ELISA Kit for Rattus norvegicus (Rat)



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