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FOLH1

FOLH1,即葉酸水解酶1,別名 Cell growth inhibiting protein 27 、Folate hydrolase 1、Folate hydrolase,是一種關(guān)鍵的葉酸代謝酶。它由FOLH1基因編碼,分布在前列腺、腦、肺、肝等多種組織中。FOLH1通過水解葉酸多聚谷氨酸鹽,調(diào)節(jié)細(xì)胞內(nèi)葉酸水平,對DNA合成和修復(fù)至關(guān)重要。其異常表達(dá)與前列腺癌等腫瘤的發(fā)生發(fā)展關(guān)聯(lián),使其成為潛在的治療靶點(diǎn)。此外,F(xiàn)OLH1在神經(jīng)退行性疾病中也有研究價(jià)值,其活性變化可能與多巴胺神經(jīng)元損失有關(guān),對細(xì)胞代謝和增殖具有重要調(diào)控作用。

熱銷產(chǎn)品

Recombinant Human Glutamate carboxypeptidase 2 (FOLH1), partial (Active) (CSB-MP008782HU1)

驗(yàn)證數(shù)據(jù)

CSB-MP008782HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP008782HU1

Activity
Measured by its binding ability in a functional ELISA.Immobilized Human FOLH1 at 2 μg/ml can bind Anti-FOLH1 recombinant antibody(CSB-RA008782MA1HU). The EC50 is 11.74-15.02 ng/mL.

CSB-MP008782HU1

Activity
Measured by its binding ability in a functional ELISA.Immobilized Human FOLH1 at 2 μg/mL can bind Anti-FOLH1 recombinant antibody(CSB-RA008782MA2HU). The EC50 is 3.853-4.303 ng/mL.

FOLH1 Recombinant Monoclonal Antibody (CSB-RA162924A0HU)

驗(yàn)證數(shù)據(jù)

CSB-RA162924A0HU

IHC image of CSB-RA162924A0HU diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

Human Glutamate carboxypeptidase 2(FOLH1) ELISA kit (CSB-EL008782HU)

驗(yàn)證數(shù)據(jù)

CSB-EL008782HU 標(biāo)準(zhǔn)曲線

貨號:CSB-EL008782HU

規(guī)格:96T/48T

靈敏度:1.2 ng/mL

檢測范圍:4.7 ng/mL-300 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

FOLH1 Antibodies

FOLH1 for Homo sapiens (Human)

FOLH1 Proteins

FOLH1 Proteins for Rattus norvegicus (Rat)

FOLH1 Proteins for Homo sapiens (Human)

FOLH1 Proteins for Mus musculus (Mouse)

FOLH1 Proteins for Sus scrofa (Pig)

FOLH1 ELISA Kit

FOLH1 ELISA Kit for Homo sapiens (Human)



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