FLNA
Filamin A（常被稱為細(xì)絲蛋白A或ABP-280）是細(xì)胞內(nèi)重要的骨架蛋白，負(fù)責(zé)維持細(xì)胞形態(tài)與調(diào)控細(xì)胞活動(dòng)。它像分子橋梁般連接肌動(dòng)蛋白纖維，穩(wěn)定細(xì)胞結(jié)構(gòu)，還參與細(xì)胞間的信號(hào)交流，影響細(xì)胞移動(dòng)、分化等過程。
FLNA異常會(huì)引發(fā)多種健康問題：部分X染色體相關(guān)遺傳病患者可能出現(xiàn)骨骼發(fā)育異常、心血管功能紊亂或神經(jīng)系統(tǒng)癥狀；此外，其突變也與腫瘤進(jìn)展有關(guān)，如某些白血病或?qū)嶓w瘤中，F(xiàn)LNA的變化可能促進(jìn)癌細(xì)胞的侵襲和轉(zhuǎn)移。目前針對(duì)FLNA相關(guān)疾病的治療仍在探索階段，研究人員嘗試通過調(diào)節(jié)其功能來干預(yù)疾病進(jìn)程，比如開發(fā)靶向它與其他蛋白相互作用的小分子藥物，但這些候選藥物大多處于實(shí)驗(yàn)室研究或早期臨床試驗(yàn)階段，尚未有成熟方案應(yīng)用于臨床。
熱銷產(chǎn)品
Recombinant Human Filamin-A (FLNA), partial (CSB-EP008724HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
FLNA Recombinant Monoclonal Antibody (CSB-RA932766A0HU)
驗(yàn)證數(shù)據(jù)
Flow cytometric analysis of FLNA expression in HepG2 cells using FLNA antibody. Green, isotype control; red, FLNA.
Western blotting analysis using FLNA antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with FLNA antibody and HRP-conjugated goat rabbit secondary antibody respectively.
FLNA Antibody (CSB-PA008724LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA008724LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA008724LA01HU at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-PA008724LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Human Filamin-A(FLNA) ELISA kit (CSB-EL008724HU)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL008724HU
規(guī)格：96T/48T
靈敏度：4.68 pg/mL
檢測(cè)范圍：18.75 pg/mL-1200 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
FLNA Antibodies
FLNA for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA000688 | Phospho-FLNA (S2152) Antibody | Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
| CSB-PA002535 | FLNA Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA985162 | FLNA Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA904028 | FLNA Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA008724LA01HU | FLNA Antibody | Human | ELISA, IHC, IF |
| CSB-PA008724LB01HU | FLNA Antibody, HRP conjugated | Human | ELISA |
| CSB-PA008724LC01HU | FLNA Antibody, FITC conjugated | Human | |
| CSB-PA008724LD01HU | FLNA Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA548809A0HU | FLNA Recombinant Monoclonal Antibody | Human | ELISA, IHC |
| CSB-RA932766A0HU | FLNA Recombinant Monoclonal Antibody | Human, Mouse, Rat | ELISA, WB, FC |
FLNA Proteins
FLNA Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP008724HU CSB-BP008724HU CSB-MP008724HU CSB-EP008724HU-B |
Recombinant Human Filamin-A (FLNA), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP008724HU | Recombinant Human Filamin-A (FLNA), partial | E.coli |
FLNA Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP804854MO CSB-BP804854MO CSB-MP804854MO CSB-EP804854MO-B |
Recombinant Mouse Filamin-A (Flna), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FLNA ELISA Kit
FLNA ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL008724HU | Human Filamin-A(FLNA) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 4.68 pg/mL |
