EDIL3
EDIL3，全稱為表皮生長(zhǎng)因子樣重復(fù)序列和類盤(pán)蛋白I樣結(jié)構(gòu)域3（EGF-like repeats and discoidin I-like domain-containing protein 3），也被稱為Del-1或MGC26287，是一種分泌蛋白，主要由內(nèi)皮細(xì)胞分泌，也由多種腫瘤細(xì)胞表達(dá)。EDIL3在胚胎發(fā)育過(guò)程中發(fā)揮重要作用，參與血管生成、抗炎和腫瘤發(fā)展等過(guò)程。研究表明，EDIL3可以通過(guò)結(jié)合整合素αvβ3促進(jìn)血管生成，并抑制內(nèi)皮細(xì)胞凋亡，從而促進(jìn)腫瘤生長(zhǎng)和轉(zhuǎn)移。此外，EDIL3還參與巨噬細(xì)胞的吞噬作用，清除凋亡細(xì)胞和血小板微粒，維持機(jī)體的健康。EDIL3在多種疾病中發(fā)揮重要作用，包括腫瘤、炎癥性疾病、動(dòng)脈粥樣硬化等。目前，針對(duì)EDIL3的藥物研發(fā)尚處于早期階段，但已有研究表明，抑制EDIL3的表達(dá)或活性可以有效抑制腫瘤生長(zhǎng)和轉(zhuǎn)移，并改善炎癥性疾病的治療效果。因此，EDIL3有望成為開(kāi)發(fā)新型藥物的重要靶點(diǎn)。
熱銷產(chǎn)品
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
EDIL3 Antibody (CSB-PA007399ESR1HU)
驗(yàn)證數(shù)據(jù)
Western blot
All lanes: EDIL3 antibody at 3.09µg/ml
Lane 1: 293T whole cell lysate
Lane 2: Hela whole cell lysate
Lane 3: HepG2 whole cell lysate
Lane 4: K562 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 54, 53 kDa
Observed band size: 54 kDa
Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA007399ESR1HU at dilution of 1:100
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL007399HU
規(guī)格：96T/48T
靈敏度：31.25 pg/mL
檢測(cè)范圍：125 pg/mL-8000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
EDIL3 Antibodies
EDIL3 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA007399GA01HU | EDIL3 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA931107 | EDIL3 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA126136 | EDIL3 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA007399ESR1HU | EDIL3 Antibody | Human | ELISA, WB, IHC |
| CSB-PA007399ESR2HU | EDIL3 Antibody | Human | ELISA, IHC |
EDIL3 Proteins
EDIL3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP007399HU CSB-EP007399HU CSB-MP007399HU CSB-EP007399HU-B |
Recombinant Human EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3) | Yeast E.coli Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-BP007399HU | Recombinant Human EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3) | Baculovirus |
EDIL3 ELISA Kit
EDIL3 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL007399HU | Human EGF-like repeat and discoidin I-like domain-containing protein 3(EDIL3) ELISA kit | serum, plasma, tissue homogenates | 31.25 pg/mL |
