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Dsg3

Dsg3(Desmoglein 3)屬于細胞粘附蛋白家族,是一種細胞表面受體。它具有多個外胞糖基化位點,這些位點可以與其他細胞粘附蛋白相互作用,從而在細胞間形成穩(wěn)定的連接。Dsg3的結(jié)構(gòu)使其能夠參與細胞間連接,維持組織的完整性。Dsg3主要在上皮細胞中發(fā)揮作用,特別是在皮膚和黏膜組織中。它的主要功能是維持上皮細胞之間的黏附力和連接。Dsg3通過與其他細胞粘附蛋白(如Dsg1和Dsc2/3)相互作用,形成了稱為沙漏連接的結(jié)構(gòu),這有助于確保細胞的互鎖和組織的完整性。失去Dsg3或其功能異??赡軐?dǎo)致一些皮膚和黏膜疾病,如皮膚大皰性疾病。Dsg3的研究對于理解皮膚和黏膜組織的發(fā)育和穩(wěn)定性至關(guān)重要。

熱銷產(chǎn)品

Recombinant Human Desmoglein-3(DSG3),partial (Active) CSB-BP007205HUc7

驗證數(shù)據(jù)

SDS
CSB-BP007205HUc7-SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA
High Purity Validated of CSB-BP007205HUc7

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human DSG3 at 2 μg/mL can bind Anti-DSG3 recombinant antibody (CSB-RA007205A0HU), the EC50 is 4.552-5.720 ng/mL.

Recombinant Mouse Desmoglein-3(Dsg3),partial (Active) CSB-MP007205MOd7

驗證數(shù)據(jù)

SDS
CSB-MP007205MOd7-SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA
High Purity Validated of CSB-MP007205MOd7

Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse Dsg3 at 5 μg/ml can bind Anti-DSG3 recombinant antibody (CSB-RA007205A0HU), the EC50 is 2.624-3.182 μg/ml.

Dsg3 Antibodies

Dsg3 for Homo sapiens (Human)

Dsg3 for Mus musculus (Mouse)

Dsg3 Proteins

Dsg3 Proteins for Homo sapiens (Human)

Dsg3 Proteins for Mus musculus (Mouse)

Dsg3 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

Dsg3 ELISA Kit

Dsg3 ELISA Kit for Homo sapiens (Human)



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