DLAT（dihydrolipoamide S-acetyltransferase）是線粒體中的蛋白質(zhì)，是α-酮戊二酸脫氫酶復(fù)合物的組成部分之一。它包含活性位點(diǎn)，能夠催化乙酰輔酶A和α-酮戊二酸之間的乙酰轉(zhuǎn)移反應(yīng)。 DLAT在三羧酸循環(huán)（TCA循環(huán)）中發(fā)揮重要作用，促進(jìn)食物分解產(chǎn)生的乙酰輔酶A與三羧酸循環(huán)中產(chǎn)生的α-酮戊二酸之間的關(guān)鍵代謝步驟。能夠?qū)⒁阴］o酶A轉(zhuǎn)移至α-酮戊二酸，促進(jìn)其進(jìn)入TCA循環(huán)，從而參與產(chǎn)生細(xì)胞能量所需的NADH和FADH2。DLAT的活性和功能對(duì)于維持正常的能量代謝過(guò)程至關(guān)重要，特別是在細(xì)胞的線粒體內(nèi)。了解DLAT在能量代謝中的作用對(duì)于理解線粒體功能異常和相關(guān)疾?。ㄈ绱x性疾?。┑陌l(fā)生具有重要意義。

熱銷產(chǎn)品

Recombinant Mouse Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (Dlat)

驗(yàn)證數(shù)據(jù)

SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

LC-MS

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP804374MOa0 could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Dlat.

LC-MS

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP804374MOa0 could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Dlat.