CXCL9

CXCL9，全稱Chemokine (C-X-C motif) ligand 9，別名MIG（Monokine induced by gamma interferon）、CMK、Humig、SCYB9、crg-10，是一種屬于CXC趨化因子家族的小分子細(xì)胞因子。它主要由多種細(xì)胞類型分泌，包括免疫細(xì)胞（如T淋巴細(xì)胞、NK細(xì)胞、樹突狀細(xì)胞、巨噬細(xì)胞、嗜酸性粒細(xì)胞等）和非免疫細(xì)胞（如肝星狀細(xì)胞、前脂肪細(xì)胞、甲狀腺細(xì)胞、內(nèi)皮細(xì)胞、腫瘤細(xì)胞和成纖維細(xì)胞等）。CXCL9與其受體CXCR3結(jié)合，能夠招募CXCR3+細(xì)胞，如效應(yīng)T細(xì)胞、調(diào)節(jié)性T細(xì)胞(Tregs)和CD8+細(xì)胞毒性T細(xì)胞，參與免疫調(diào)節(jié)和炎癥過程。此外，CXCL9還在腫瘤生長、血管生成和轉(zhuǎn)移中發(fā)揮關(guān)鍵作用。研究表明，CXCL9能夠介導(dǎo)淋巴細(xì)胞浸潤至病灶部位并抑制腫瘤生長，其吸引CXCR3-（CXCR3-A和CXCR3-B）T淋巴細(xì)胞，參與多種生理疾病的發(fā)生和維持的發(fā)病機(jī)制。在藥物研發(fā)方面，有研究指出，通過靶向調(diào)控胱氨酸代謝可顯著增強(qiáng)免疫檢查點(diǎn)抑制劑（ICIs）的效果，為肺癌治療帶來新的希望。

熱銷產(chǎn)品

Recombinant Human C-X-C motif chemokine 9 (Cxcl9) (CSB-EP006252HU)

驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CXCL9 Antibody (CSB-PA06189A0Rb)

驗(yàn)證數(shù)據(jù)

IHC image of CSB-PA06189A0Rb diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Human monocyte interferon gamma inducing factor,MIG ELISA Kit (CSB-E09024h)

驗(yàn)證數(shù)據(jù)

貨號：CSB-E09024h

規(guī)格：96T/48T

靈敏度：9.75 pg/ml.

檢測范圍：39 pg/ml-2500 pg/ml.

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

CXCL9 Antibody

CXCL9 Protein

CXCL9 ELISA Kit

CXCL9 Antibodies

CXCL9 for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA09269A0Rb	Cxcl9 Antibody	Mouse	ELISA
CSB-PA09269D0Rb	Cxcl9 Antibody, Biotin conjugated	Mouse	ELISA

CXCL9 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA959979	CXCL9 Antibody	Human	IHC,ELISA
CSB-PA06189A0Rb	CXCL9 Antibody	Human	ELISA, IHC

CXCL9 Proteins

CXCL9 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP006252MO CSB-BP006252MO CSB-MP006252MO CSB-EP006252MO-B	Recombinant Mouse C-X-C motif chemokine 9 (Cxcl9)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006252MO	Recombinant Mouse C-X-C motif chemokine 9 (Cxcl9)	E.coli
CSB-AP001131MO	Recombinant Mouse C-X-C motif chemokine 9 protein (Cxcl9), partial (Active)	E.Coli

CXCL9 Proteins for Bos taurus (Bovine)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP006252BO CSB-EP006252BO CSB-BP006252BO CSB-MP006252BO CSB-EP006252BO-B	Recombinant Bovine C-X-C motif chemokine 9 (CXCL9)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CXCL9 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-AP000711HU	Recombinant Human C-X-C motif chemokine 9 protein (CXCL9)	E.Coli
CSB-EP006252HU	Recombinant Human C-X-C motif chemokine 9 (Cxcl9)	E.coli
CSB-EP006252HUc7	Recombinant Human C-X-C motif chemokine 9 (Cxcl9)	E.coli