CXCL3
CXCL3，全稱為C-X-C motif chemokine ligand 3，是一種小分子細(xì)胞因子，屬于CXC趨化因子家族。它也被稱為GRO3、GRO蛋白γ（GROg）和巨噬細(xì)胞炎癥因子MIP-2。CXCL3主要由巨噬細(xì)胞釋放，在炎癥過(guò)程中發(fā)揮重要作用。它能夠吸引中性粒細(xì)胞向炎癥部位遷移，并參與腫瘤細(xì)胞的生長(zhǎng)、增殖、轉(zhuǎn)移和血管生成。CXCL3通過(guò)與CXCR2受體結(jié)合，激活下游信號(hào)通路，促進(jìn)細(xì)胞遷移和炎癥反應(yīng)。研究表明，CXCL3的高表達(dá)與多種疾病的發(fā)生發(fā)展密切相關(guān)，包括結(jié)直腸癌、胰腺癌、腦膠質(zhì)瘤等。在結(jié)直腸癌中，CXCL3的高表達(dá)與患者的預(yù)后不良相關(guān)。因此，CXCL3成為疾病診斷和治療的潛在靶點(diǎn)。目前，針對(duì)CXCL3的藥物研發(fā)正在積極進(jìn)行中，包括CXCR2抑制劑和CXCL3中和抗體等。這些藥物有望為相關(guān)疾病的治療提供新的選擇。
熱銷產(chǎn)品
CXCL3 Antibody (CSB-PA08999A0Rb)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA08999A0Rb at dilution of 1:100
Human C-X-C motif chemokine 3(CXCL3) ELISA kit (CSB-EL006249HU)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL006249HU
規(guī)格：96T/48T
靈敏度：2.34 pg/mL
檢測(cè)范圍：9.37 pg/mL-600 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CXCL3 Antibodies
CXCL3 for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA09239A0Rb | Cxcl3 Antibody | Mouse | ELISA |
CXCL3 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA006249GA01HU | CXCL3 Antibody | Human | ELISA,IHC |
| CSB-PA009037 | CXCL3 Antibody | Human | IHC, ELISA |
| CSB-PA273344 | CXCL3 Antibody | Human | ELISA,IHC |
| CSB-PA293996 | CXCL3 Antibody | Human | ELISA,IHC |
| CSB-PA08999A0Rb | CXCL3 Antibody | Human | ELISA, IHC |
| CSB-PA08999B0Rb | CXCL3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA08999C0Rb | CXCL3 Antibody, FITC conjugated | Human | |
| CSB-PA08999D0Rb | CXCL3 Antibody, Biotin conjugated | Human | ELISA |
CXCL3 Proteins
CXCL3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP006249HU CSB-BP006249HU CSB-MP006249HU CSB-EP006249HU-B |
Recombinant Human C-X-C motif chemokine 3 (CXCL3) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP006249HU | Recombinant Human C-X-C motif chemokine 3 (CXCL3) | E.coli |
| CSB-AP000651HU | Recombinant Human C-X-C motif chemokine 3 protein (CXCL3) | E.Coli |
| CSB-AP003551HU | Recombinant Human C-X-C motif chemokine 3 (CXCL3) (Active) | E.coli |
CXCL3 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP608835RA CSB-EP608835RA CSB-BP608835RA CSB-MP608835RA CSB-EP608835RA-B |
Recombinant Rat C-X-C motif chemokine 3 (Cxcl3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP001411RA | Recombinant Rat C-X-C motif chemokine 3 protein (Cxcl3) | E.Coli |
| CSB-AP001421RA | Recombinant Rat C-X-C motif chemokine 3 protein (Cxcl3), partial (Active) | E.Coli |
CXCL3 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP744293MO CSB-EP744293MO CSB-BP744293MO CSB-MP744293MO CSB-EP744293MO-B |
Recombinant Mouse C-X-C motif chemokine 3 (Cxcl3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-RP092394m | Recombinant Mouse C-X-C motif chemokine 3 protein (Cxcl3) | E.coli |
| CSB-AP001091MO | Recombinant Mouse C-X-C motif chemokine 3 protein (Cxcl3), partial (Active) | E.Coli |
CXCL3 ELISA Kit
CXCL3 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL006249HU | Human C-X-C motif chemokine 3(CXCL3) ELISA kit | serum, plasma, tissue homogenates | 2.34 pg/mL |
CXCL3 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL006249MO | Mouse C-X-C motif chemokine 3(CXCL3) ELISA kit | serum, plasma, tissue homogenates | 1.56 pg/mL |
CXCL3 ELISA Kit for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL006249RA | Rat C-X-C motif chemokine 3(CXCL3) ELISA kit | serum, plasma, tissue homogenates | 3.9 pg/ml |
