CPN2
CAPN2（Calpain-2）是一種半胱氨酸蛋白酶，全稱為鈣蛋白酶-2，別名為Mu-calpain或Capn2。該蛋白參與細(xì)胞信號(hào)調(diào)控、蛋白質(zhì)降解和細(xì)胞凋亡等過程，在神經(jīng)系統(tǒng)和肌肉組織中發(fā)揮重要作用。CAPN2通過水解靶蛋白，影響細(xì)胞功能，與多種生理病理過程相關(guān)。研究表明，CAPN2異常表達(dá)或活性失衡與神經(jīng)退行性疾病（如阿爾茨海默?。?、癌癥和自身免疫性疾病等有關(guān)。在藥物研發(fā)方面，針對(duì)CAPN2的抑制劑和激活劑正被探索用于治療相關(guān)疾病。例如，BTM-3566是一種靶向OMA1和CAPN2的抗癌新藥，已在臨床試驗(yàn)中展示潛力。此外，多靶點(diǎn)藥物和多特異性抗體等創(chuàng)新療法也關(guān)注CAPN2的作用，為疾病治療提供新思路。隨著研究的深入，CAPN2相關(guān)藥物有望為神經(jīng)退行性疾病和癌癥患者帶來(lái)更多臨床獲益。
熱銷產(chǎn)品
Recombinant Human Carboxypeptidase N subunit 2 (CPN2) (CSB-EP005899HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Human Carboxypeptidase N subunit 2(CPN2) ELISA kit (CSB-EL005899HU)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL005899HU
規(guī)格：96T/48T
靈敏度：0.039 ng/mL
檢測(cè)范圍：0.156 ng/mL-10 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CPN2 Antibodies
CPN2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA276934 | CPN2 Antibody | Human | ELISA,WB |
| CSB-PA007245 | CPN2 Antibody | Human | WB, ELISA |
CPN2 Proteins
CPN2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP005899HU CSB-BP005899HU CSB-EP005899HU-B |
Recombinant Human Carboxypeptidase N subunit 2 (CPN2) | Yeast Baculovirus In Vivo Biotinylation in E.coli |
| CSB-EP005899HU | Recombinant Human Carboxypeptidase N subunit 2 (CPN2) | E.coli |
| CSB-MP005899HU | Recombinant Human Carboxypeptidase N subunit 2 (CPN2) | Mammalian cell |
CPN2 ELISA Kit
CPN2 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL005899HU | Human Carboxypeptidase N subunit 2(CPN2) ELISA kit | serum, plasma, tissue homogenates | 0.039 ng/mL |
