CNR1
CNR1，全稱(chēng)為是大麻素受體1型，常被稱(chēng)為CB1受體，是內(nèi)源性大麻素系統(tǒng)的核心成員之一。它廣泛分布于大腦中調(diào)控情緒、記憶和獎(jiǎng)賞的區(qū)域，外周脂肪、肝臟等組織也有少量存在。當(dāng)與體內(nèi)自然產(chǎn)生的大麻素或植物來(lái)源的大麻素結(jié)合時(shí)，CB1受體能參與調(diào)節(jié)多種生理過(guò)程，比如緩解疼痛感知、影響食欲控制與能量代謝，還和情緒狀態(tài)的穩(wěn)定密切相關(guān)。
CNR1功能異?？赡芘c焦慮障礙、慢性疼痛綜合征、肥胖癥及藥物依賴(lài)等問(wèn)題關(guān)聯(lián)。目前針對(duì)CB1受體的藥物研發(fā)持續(xù)推進(jìn)，早期部分藥物因可能引發(fā)精神狀態(tài)改變等副作用受限，現(xiàn)在研究更聚焦于選擇性更強(qiáng)的調(diào)節(jié)劑，希望精準(zhǔn)改善疼痛或代謝紊亂的同時(shí)減少副作用，不少候選藥物已進(jìn)入臨床試驗(yàn)階段。
熱銷(xiāo)產(chǎn)品
Recombinant Human Cannabinoid receptor 1 (CNR1)-VLPs (Active) (CSB-MP005678HU)
驗(yàn)證數(shù)據(jù)
CSB-MP005678HU is detected by Mouse anti-6*His monoclonal antibody.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human CNR1 at 10 μg/ml can bind Anti-CNR1 recombinant antibody (CSB-RA005678MA01HU), the EC50 is 41.72-63.54 ng/mL.
CNR1 Recombinant Monoclonal Antibody (CSB-RA005678MA01HU)
驗(yàn)證數(shù)據(jù)
The Binding Activity of Huamn CNR1 with Anti-CNR1 recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CNR1(CSB-MP005678HU) at 10 μg/mL can bind Anti-CNR1 recombinant antibody, the EC50 is 41.72-63.54 ng/mL.
CNR1 Antibodies
CNR1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA005678GA01HU | CNR1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA007048 | CNR1 Antibody | Human,Mouse,Rat,Monkey | WB, IHC, IF, ELISA |
| CSB-PA005678LA01HU | CNR1 Antibody | Human | ELISA, WB |
| CSB-PA005678LB01HU | CNR1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA005678LC01HU | CNR1 Antibody, FITC conjugated | Human | |
| CSB-PA005678LD01HU | CNR1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA005678MA01HU | CNR1 Recombinant Monoclonal Antibody | Human | ELISA |
CNR1 Proteins
CNR1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP005678HU1 CSB-EP005678HU1 CSB-BP005678HU1 CSB-MP005678HU1 CSB-EP005678HU1-B |
Recombinant Human Cannabinoid receptor 1 (CNR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF005678HU | Recombinant Human Cannabinoid receptor 1 (CNR1) | in vitro E.coli expression system |
| CSB-MP005678HU | Recombinant Human Cannabinoid receptor 1 (CNR1)-VLPs (Active) | Mammalian cell |
CNR1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP005678RA1 CSB-EP005678RA1 CSB-BP005678RA1 CSB-MP005678RA1 CSB-EP005678RA1-B |
Recombinant Rat Cannabinoid receptor 1 (Cnr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF005678RA | Recombinant Rat Cannabinoid receptor 1 (CNR1) | in vitro E.coli expression system |
CNR1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP005678MO1 CSB-EP005678MO1 CSB-BP005678MO1 CSB-MP005678MO1 CSB-EP005678MO1-B |
Recombinant Mouse Cannabinoid receptor 1 (Cnr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF005678MO | Recombinant Mouse Cannabinoid receptor 1 (Cnr1) | in vitro E.coli expression system |
CNR1 Proteins for Felis catus (Cat) (Felis silvestris catus)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP005678CA1 CSB-EP005678CA1 CSB-BP005678CA1 CSB-MP005678CA1 CSB-EP005678CA1-B |
Recombinant Cat Cannabinoid receptor 1 (CNR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF005678CA | Recombinant Cat Cannabinoid receptor 1 (CNR1) | in vitro E.coli expression system |
CNR1 Proteins for Taeniopygia guttata (Zebra finch) (Poephila guttata)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP005678TKW1 CSB-EP005678TKW1 CSB-BP005678TKW1 CSB-MP005678TKW1 CSB-EP005678TKW1-B |
Recombinant Taeniopygia guttata Cannabinoid receptor 1 (CNR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF005678TKW | Recombinant Taeniopygia guttata Cannabinoid receptor 1 (CNR1) | in vitro E.coli expression system |
CNR1 Proteins for Zea mays (Maize)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP469624ZAX1 CSB-EP469624ZAX1 CSB-BP469624ZAX1 CSB-MP469624ZAX1 CSB-EP469624ZAX1-B |
Recombinant Zea mays Cell number regulator 1 (CNR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF469624ZAX | Recombinant Zea mays Cell number regulator 1 (CNR1) | in vitro E.coli expression system |
CNR1 Proteins for Rana esculenta (Edible frog) (Pelophylax esculentus)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP657029RAW1 CSB-EP657029RAW1 CSB-BP657029RAW1 CSB-MP657029RAW1 CSB-EP657029RAW1-B |
Recombinant Rana esculenta Cannabinoid receptor 1 (cnr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF657029RAW | Recombinant Rana esculenta Cannabinoid receptor 1 (cnr1) | in vitro E.coli expression system |
CNR1 Proteins for Pan troglodytes (Chimpanzee)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP683301EQV1 CSB-EP683301EQV1 CSB-BP683301EQV1 CSB-MP683301EQV1 CSB-EP683301EQV1-B |
Recombinant Pan troglodytes Cannabinoid receptor 1 (CNR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF683301EQV | Recombinant Pan troglodytes Cannabinoid receptor 1 (CNR1) | in vitro E.coli expression system |
CNR1 Proteins for Macaca mulatta (Rhesus macaque)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP758268MOW1 CSB-EP758268MOW1 CSB-BP758268MOW1 CSB-MP758268MOW1 CSB-EP758268MOW1-B |
Recombinant Macaca mulatta Cannabinoid receptor 1 (CNR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF758268MOW | Recombinant Macaca mulatta Cannabinoid receptor 1 (CNR1) | in vitro E.coli expression system |
CNR1 Proteins for Xenopus laevis (African clawed frog)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP770415XBE1 CSB-EP770415XBE1 CSB-BP770415XBE1 CSB-MP770415XBE1 CSB-EP770415XBE1-B |
Recombinant Xenopus laevis Cannabinoid receptor 1 (cnr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF770415XBE | Recombinant Xenopus laevis Cannabinoid receptor 1 (cnr1) | in vitro E.coli expression system |
CNR1 Proteins for Taricha granulosa (Roughskin newt)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP874041TAX1 CSB-EP874041TAX1 CSB-BP874041TAX1 CSB-MP874041TAX1 CSB-EP874041TAX1-B |
Recombinant Taricha granulosa Cannabinoid receptor 1 (CNR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF874041TAX | Recombinant Taricha granulosa Cannabinoid receptor 1 (CNR1) | in vitro E.coli expression system |
