CLEC6A
CLEC6A，全稱(chēng)為C型凝集素結(jié)構(gòu)域家族6成員A，常見(jiàn)別名包括Dectin-2、C-type lectin domain family 6 member A、CLECSF10、CLEC6A、CLEC4N等。該蛋白屬于C型凝集素受體家族，主要表達(dá)于免疫細(xì)胞表面，如巨噬細(xì)胞、樹(shù)突狀細(xì)胞和中性粒細(xì)胞等。CLEC6A蛋白能夠識(shí)別病原體表面的糖類(lèi)分子，如β-葡聚糖，從而在先天免疫中發(fā)揮重要作用。它通過(guò)識(shí)別真菌細(xì)胞壁成分激活下游信號(hào)通路，觸發(fā)炎癥因子釋放和吞噬作用，幫助機(jī)體防御真菌感染。CLEC6A蛋白的表達(dá)異?？赡芘c慢性黏膜皮膚念珠菌病等真菌易感性疾病相關(guān)，而過(guò)度激活則可能與自身免疫疾病或炎癥性疾病相關(guān)。目前，針對(duì)CLEC6A蛋白的藥物研發(fā)主要集中在免疫調(diào)節(jié)和抗感染領(lǐng)域，例如開(kāi)發(fā)能夠特異性結(jié)合CLEC6A蛋白的抗體或小分子化合物，以調(diào)節(jié)免疫反應(yīng)或增強(qiáng)機(jī)體抗感染能力。
熱銷(xiāo)產(chǎn)品
CLEC4A Antibody (CSB-PA412681)
驗(yàn)證數(shù)據(jù)
Western Blot analysis of HEPG2 cells using CLECSF6 Polyclonal Antibody diluted at 1:500. Secondary antibody was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded human-colon-cancer, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-colon-cancer, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
CLEC6A Antibodies
CLEC6A for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA181586 | CLEC4A Antibody | Human,Mouse | ELISA,WB |
| CSB-PA016840 | CLEC4A Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA412681 | CLEC4A Antibody | Human | WB,ELISA |
CLEC6A Proteins
CLEC6A Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP891558HU CSB-EP891558HU CSB-BP891558HU CSB-MP891558HU CSB-EP891558HU-B |
Recombinant Human C-type lectin domain family 4 member A (CLEC4A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
