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CHGA

嗜鉻粒蛋白A是CHGA基因表達(dá)的蛋白,全名Chromogranin A,常見別名CGA。它廣泛存在于神經(jīng)內(nèi)分泌細(xì)胞與神經(jīng)細(xì)胞中,能參與生成血管活性腸肽、嗜鉻粒蛋白衍生肽等多種活性物質(zhì),這些物質(zhì)可調(diào)節(jié)血管張力、激素分泌等生理過程。
臨床中,它是神經(jīng)內(nèi)分泌腫瘤的重要標(biāo)志物——嗜鉻細(xì)胞瘤、胃腸胰神經(jīng)內(nèi)分泌腫瘤患者體內(nèi)其水平常顯著升高,可用于疾病診斷與病情監(jiān)測。此外,它和高血壓、心力衰竭等心血管疾病也有關(guān)聯(lián),部分患者體內(nèi)含量會出現(xiàn)異常變化。藥物研發(fā)方面,基于它的檢測試劑盒已用于臨床腫瘤篩查;針對它的靶向藥物處于早期研發(fā)階段,希望通過調(diào)節(jié)相關(guān)生理過程,為神經(jīng)內(nèi)分泌腫瘤或心血管疾病提供新的治療思路。

熱銷產(chǎn)品

Recombinant Human Chromogranin-A (CHGA) (CSB-MP005344HU)

驗(yàn)證數(shù)據(jù)

CSB-MP005344HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CHGA Monoclonal Antibody (CSB-MA048978)

驗(yàn)證數(shù)據(jù)

CSB-MA048978

Immunocytochemical staining of HAP-1 cells with Chromogranin A antibody. Nuclei were stained blue with DAPI; Chromogranin A was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 μm.

CSB-MA048978

Western blotting analysis using chromogranin A antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with chromogranin A antibody and HRP-conjugated goat anti-mouse secondary antibody respectively.

CHGA Antibody (CSB-PA005344YA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA005344YA01HU

Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA005344YA01HU at dilution of 1:100

CSB-PA005344YA01HU

Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA005344YA01HU at dilution of 1:100

Human Chromogranin,CgA ELISA Kit (CSB-E09153h)

驗(yàn)證數(shù)據(jù)

CSB-E09153h 標(biāo)準(zhǔn)曲線

貨號:CSB-E09153h

規(guī)格:96T/48T

靈敏度:15.6 ng/mL

檢測范圍:62.5 ng/mL-4000 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

CHGA Antibodies

CHGA for Homo sapiens (Human)

CHGA Proteins

CHGA Proteins for Rattus norvegicus (Rat)

CHGA Proteins for Homo sapiens (Human)

CHGA Proteins for Mus musculus (Mouse)

CHGA Proteins for Bos taurus (Bovine)

CHGA Proteins for Sus scrofa (Pig)

CHGA Proteins for Struthio camelus (Ostrich)

CHGA Proteins for Equus caballus (Horse)

CHGA ELISA Kit

CHGA ELISA Kit for Homo sapiens (Human)



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