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CD72

CD72,全稱為CD72蛋白,也被稱為Lyb-2或Lyb2。該蛋白在B細胞增殖和分化中扮演關(guān)鍵角色,與CD5相互作用,形成具有二硫鍵的同二聚體。CD72蛋白通過酪氨酸磷酸化與PTPN6/SHP-1相互作用,調(diào)節(jié)細胞反應(yīng)。CD72蛋白與B細胞活化和免疫反應(yīng)密切相關(guān),其功能異常可能與多種疾病有關(guān),如腫瘤和自身免疫性疾病。在藥物研發(fā)方面,針對CD72的抑制劑正在開發(fā)中,旨在調(diào)節(jié)B細胞介導(dǎo)的免疫過程,以治療相關(guān)疾病。

熱銷產(chǎn)品

Recombinant Human B-cell differentiation antigen CD72 (CD72), partial (CSB-MP004955HU1)

驗證數(shù)據(jù)

CSB-MP004955HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CD72 Antibody (CSB-PA004955LA01HU)

驗證數(shù)據(jù)

CSB-PA004955LA01HU

Western Blot
Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate
All lanes: CD72 antibody at 3.2µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 41 kDa
Observed band size: 41 kDa

CSB-PA004955LA01HU

Immunofluorescence staining of Hela cells with CSB-PA004955LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Human B-cell differentiation antigen CD72(CD72) ELISA kit (CSB-EL004955HU)

驗證數(shù)據(jù)

CSB-EL004955HU 標(biāo)準(zhǔn)曲線

貨號:CSB-EL004955HU

規(guī)格:96T/48T

靈敏度:0.225 ng/mL

檢測范圍:0.9 ng/mL-60 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

CD72 Antibodies

CD72 for Homo sapiens (Human)

CD72 Proteins

CD72 Proteins for Mus musculus (Mouse)

CD72 Proteins for Homo sapiens (Human)

CD72 ELISA Kit

CD72 ELISA Kit for Homo sapiens (Human)



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