CD3D
CD3D，即分化簇3D，別名CD3d、T3D。它主要來(lái)源于T淋巴細(xì)胞，是TCR-CD3復(fù)合物的關(guān)鍵組成部分。CD3D在TCR接合時(shí)，通過(guò)CD3D、CD3E、CD3G和CD3Z鏈傳輸信號(hào)。這些鏈的胞質(zhì)結(jié)構(gòu)域中包含基于免疫受體酪氨酸的激活基序（ITAM），當(dāng)TCR被抗原呈遞細(xì)胞激活后，ITAM被Src家族蛋白酪氨酸激酶磷酸化，從而激活下游信號(hào)通路。CD3D不僅在T細(xì)胞激活的信號(hào)轉(zhuǎn)導(dǎo)中發(fā)揮作用，還對(duì)胸腺細(xì)胞分化至關(guān)重要，有助于TCR-CD3復(fù)合物的正確細(xì)胞內(nèi)組裝和表面表達(dá)。CD3D還與輔助受體CD4和CD8相互作用，在TCR和輔助受體之間建立功能聯(lián)系，對(duì)CD4或CD8T細(xì)胞的激活和陽(yáng)性選擇至關(guān)重要。
熱銷(xiāo)產(chǎn)品
CD3D Recombinant Monoclonal Antibody (CSB-RA004930MA1HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: Jurkat whole cell lysate
All lanes: CD3D antibody at 1:1000
Secondary
Goat polyclonal to human IgG at 1/50000 dilution
Predicted band size: 19 kDa
Observed band size: 19 kDa
CD3D Antibodies
CD3D for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA004930GA01HU | CD3D Antibody | Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA004930ESR1HU | CD3D Antibody | Human | ELISA, IHC |
| CSB-PA001452 | CD3D Antibody | Human | WB, ELISA |
| CSB-PA005826 | CD3D Antibody | Human | WB, ELISA |
| CSB-RA004930MA1HU | CD3D Recombinant Monoclonal Antibody | Human | ELISA, WB |
CD3D Proteins
CD3D Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP004930RA1 CSB-EP004930RA1 CSB-BP004930RA1 CSB-MP004930RA1 CSB-EP004930RA1-B |
Recombinant Rat T-cell surface glycoprotein CD3 delta chain (Cd3d), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004930RA | Recombinant Rat T-cell surface glycoprotein CD3 delta chain (Cd3d) | in vitro E.coli expression system |
CD3D Proteins for Ovis aries (Sheep)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP004930SH1 CSB-EP004930SH1 CSB-BP004930SH1 CSB-MP004930SH1 CSB-EP004930SH1-B |
Recombinant Sheep T-cell surface glycoprotein CD3 delta chain (CD3D), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004930SH | Recombinant Sheep T-cell surface glycoprotein CD3 delta chain (CD3D) | in vitro E.coli expression system |
CD3D Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP004930HU1 CSB-EP004930HU1 CSB-BP004930HU1 CSB-MP004930HU1 CSB-EP004930HU1-B |
Recombinant Human T-cell surface glycoprotein CD3 delta chain (CD3D), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004930HU | Recombinant Human T-cell surface glycoprotein CD3 delta chain (CD3D) | in vitro E.coli expression system |
CD3D Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP004930MO1 CSB-EP004930MO1 CSB-BP004930MO1 CSB-MP004930MO1 CSB-EP004930MO1-B |
Recombinant Mouse T-cell surface glycoprotein CD3 delta chain (Cd3d), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004930MO | Recombinant Mouse T-cell surface glycoprotein CD3 delta chain (Cd3d) | in vitro E.coli expression system |
CD3D Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP635680BO CSB-EP635680BO CSB-BP635680BO CSB-MP635680BO CSB-EP635680BO-B |
Recombinant Bovine T-cell surface glycoprotein CD3 delta chain (CD3D), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD3D Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP748460PI CSB-EP748460PI CSB-BP748460PI CSB-MP748460PI CSB-EP748460PI-B |
Recombinant Pig T-cell surface glycoprotein CD3 delta chain (CD3D), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD3D Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP853307MOV CSB-EP853307MOV CSB-BP853307MOV CSB-MP853307MOV CSB-EP853307MOV-B |
Recombinant Macaca fascicularis T-cell surface glycoprotein CD3 delta chain (CD3D), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
