CCL1
CCL1，即C-C基序趨化因子配體1，別名I-309、P500、SCYA1、SISe、TCA3。CCL1是一種小糖蛋白，屬于CC趨化因子家族，分子量約為15-16 kDa。它由活化的單核細(xì)胞、巨噬細(xì)胞、T淋巴細(xì)胞和內(nèi)皮細(xì)胞分泌，對單核細(xì)胞具有趨化性，但對中性粒細(xì)胞無趨化作用。CCL1通過與細(xì)胞表面趨化因子受體CCR8相互作用，激活鈣離子流入，刺激單核細(xì)胞中細(xì)胞質(zhì)游離鈣濃度的短暫增加，并通過RAS/MAPK途徑抑制胸腺細(xì)胞系的細(xì)胞凋亡。CCL1通過白細(xì)胞募集參與炎癥過程，并在血管生成、病毒感染以及腫瘤發(fā)生等過程中發(fā)揮關(guān)鍵作用。CCL1基因中的一些單核苷酸多態(tài)性（SNP）與慢性阻塞性肺?。–OPD）的進(jìn)展有關(guān)，CCL1在多種中樞神經(jīng)系統(tǒng)功能和疾病中發(fā)揮作用，與神經(jīng)炎癥障礙疾病相關(guān)。
熱銷產(chǎn)品
Recombinant Human C-C motif chemokine 1 (CCL1) (CSB-EP004774HUg4)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
驗(yàn)證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA079873(CCL1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA079873(CCL1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
CCL1 Antibodies
CCL1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA079873 | CCL1 Antibody | Human | ELISA,IHC |
CCL1 Proteins
CCL1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP004774MO CSB-EP004774MO CSB-BP004774MO CSB-MP004774MO CSB-EP004774MO-B |
Recombinant Mouse C-C motif chemokine 1 (Ccl1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CCL1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP004774HU CSB-BP004774HU |
Recombinant Human C-C motif chemokine 1 (CCL1) | Yeast Baculovirus |
| CSB-AP000811HU | Recombinant?Human?C-C?motif?chemokine?1 (CCL1), partial? (Active) | E.Coli |
| CSB-EP004774HU | Recombinant Human C-C motif chemokine 1 (CCL1) | E.coli |
| CSB-EP004774HUg4 | Recombinant Human C-C motif chemokine 1 (CCL1) | E.coli |
| CSB-EP004774HU-B | Recombinant Human C-C motif chemokine 1 (CCL1),Biotinylated | E.coli |
| CSB-MP004774HU | Recombinant Human C-C motif chemokine 1 (CCL1) | Mammalian cell |
CCL1 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP327665SVG CSB-EP327665SVG CSB-BP327665SVG CSB-MP327665SVG CSB-EP327665SVG-B |
Recombinant Saccharomyces cerevisiae Cyclin CCL1 (CCL1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CCL1 ELISA Kit
CCL1 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL004774HU | Human C-C motif chemokine 1(CCL1) ELISA kit | serum, plasma, tissue homogenates | 3.9 pg/ml |
CCL1 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E14298m | Mouse chemokine (C-C motif) ligand 1 ELISA Kit | serum, plasma, tissue homogenates | 1.95 pg/ml |
