ADGRL2
ADGRL2，全稱為adhesion G protein-coupled receptor L2，也被稱為L(zhǎng)PHN2或latrophilin 2。這是一種黏附類(lèi)G蛋白偶聯(lián)受體，主要參與細(xì)胞結(jié)構(gòu)的構(gòu)成和多項(xiàng)細(xì)胞生命活動(dòng)，如細(xì)胞黏附、遷移、物質(zhì)運(yùn)輸、細(xì)胞分化和凋亡等。ADGRL2在多種細(xì)胞類(lèi)型中表達(dá)，包括內(nèi)皮細(xì)胞、神經(jīng)元和免疫細(xì)胞。其與α-latrotoxin等配體結(jié)合，通過(guò)G蛋白信號(hào)通路介導(dǎo)細(xì)胞內(nèi)信號(hào)轉(zhuǎn)導(dǎo)。ADGRL2的表達(dá)與心血管疾病、神經(jīng)系統(tǒng)發(fā)育和疾病以及腫瘤發(fā)生和發(fā)展相關(guān)，因此成為藥物研發(fā)的重要靶點(diǎn)。目前，針對(duì)ADGRL2的藥物研發(fā)主要集中在調(diào)節(jié)其活性，以治療相關(guān)疾病。
熱銷(xiāo)產(chǎn)品
ADGRL2 Antibody (CSB-PA013060ESR2HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA013060ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA013060ESR2HU at dilution of 1:100
ADGRL2 Antibodies
ADGRL2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA008347 | LPHN2 Antibody | Human,Mouse,Rat | IHC, IF, ELISA |
| CSB-PA013060ESR2HU | ADGRL2 Antibody | Human | ELISA, IHC |
ADGRL2 Proteins
ADGRL2 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP013060BO CSB-EP013060BO CSB-BP013060BO CSB-MP013060BO CSB-EP013060BO-B |
Recombinant Bovine Latrophilin-2 (LPHN2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ADGRL2 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP013060RA CSB-EP013060RA CSB-BP013060RA CSB-MP013060RA CSB-EP013060RA-B |
Recombinant Rat Latrophilin-2 (Lphn2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ADGRL2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP013060HU CSB-EP013060HU CSB-BP013060HU CSB-MP013060HU CSB-EP013060HU-B |
Recombinant Human Latrophilin-2 (LPHN2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ADGRL2 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP811675MO CSB-EP811675MO CSB-BP811675MO CSB-MP811675MO CSB-EP811675MO-B |
Recombinant Mouse Latrophilin-2 (Lphn2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
