TRBV9 (Seniprutug Biosimilar) Recombinant Monoclonal Antibody
-
貨號(hào):CSB-RA7153MB1HU
-
規(guī)格:¥83486
-
其他:
產(chǎn)品詳情
-
產(chǎn)品描述:TRBV9(Seniprutug Biosimilar Antibody)重組單克隆抗體是一種用于科研領(lǐng)域的生物試劑。該抗體通過(guò)重組技術(shù)制備,具有高度的特異性和親和力,能夠精準(zhǔn)識(shí)別并結(jié)合目標(biāo)分子。在免疫學(xué)、分子生物學(xué)等研究領(lǐng)域,它可作為重要的工具,助力科研人員深入探究相關(guān)生物學(xué)機(jī)制。其獨(dú)特的結(jié)構(gòu)設(shè)計(jì)使其在實(shí)驗(yàn)中展現(xiàn)出穩(wěn)定的性能,為研究提供可靠的數(shù)據(jù)支持??蒲腥藛T可利用該抗體進(jìn)行蛋白質(zhì)檢測(cè)、細(xì)胞定位、信號(hào)通路分析等多種實(shí)驗(yàn)操作,推動(dòng)相關(guān)領(lǐng)域的研究進(jìn)展。作為科研用試劑,它為探索生命科學(xué)的奧秘提供了有力的支持,有助于拓展研究思路和發(fā)現(xiàn)新的科學(xué)現(xiàn)象。
-
Uniprot No.:
-
基因名:TRBV9
-
別名:BCD180 research-grade biosimilar; BCD 180 research-grade biosimilar; BCD-180 research-grade biosimilar ;TRBV9 antibody; T cell receptor beta variable 9 antibody
-
反應(yīng)種屬:Human
-
免疫原:Recombinant Human TRBV9 protein
-
免疫原種屬:Homo sapiens (Human)
-
標(biāo)記方式:Non-conjugated
-
克隆類型:Monoclonal
-
濃度:It differs from different batches. Please contact us to confirm it.
-
保存緩沖液:0.01M PBS,pH7.4
-
產(chǎn)品提供形式:Liquid
-
應(yīng)用說(shuō)明:Validation Status
Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
Guaranteed Quality
① Antibody purity?> 95% tested by SDS-PAGE.
② Endotoxin level < 0.1EU/ug tested by LAL method. -
儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期:3-4 weeks
-
用途:It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
-
功能:V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens. Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation. The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity.
-
亞細(xì)胞定位:Cell membrane.
-
數(shù)據(jù)庫(kù)鏈接:
HGNC: 12246
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-















