TNFSF（Sofusa anti-TNF Biosimilar Antibody)重組單克隆抗體是一種專為科研用途開發(fā)的生物制劑。該產(chǎn)品基于先進(jìn)的重組DNA技術(shù)制備，通過特異性靶向腫瘤壞死因子（TNF）發(fā)揮生物學(xué)作用。作為一款重組單克隆抗體，其具有高度均一的分子結(jié)構(gòu)和明確的抗原結(jié)合特性，為炎癥相關(guān)疾病的機(jī)制研究、藥物靶點(diǎn)驗(yàn)證以及體外藥效評(píng)價(jià)等科研工作提供可靠工具。 該抗體通過精準(zhǔn)識(shí)別TNF分子的特定表位，可在體外實(shí)驗(yàn)中高效阻斷TNF與其受體的相互作用，從而為探討TNF信號(hào)通路在免疫調(diào)節(jié)、炎癥反應(yīng)及相關(guān)疾病發(fā)生發(fā)展中的作用機(jī)制提供有力支持。產(chǎn)品嚴(yán)格按照科研級(jí)標(biāo)準(zhǔn)生產(chǎn)，經(jīng)過多輪純化和質(zhì)量檢測(cè)，確保批次間的穩(wěn)定性和一致性，適用于細(xì)胞實(shí)驗(yàn)、蛋白結(jié)合分析、 ELISA檢測(cè)等多種實(shí)驗(yàn)場(chǎng)景。 作為研究工具，TNFSF重組單克隆抗體有助于科研人員深入探索TNF介導(dǎo)的生物學(xué)過程，為開發(fā)新型抗炎藥物或治療策略提供前期研究基礎(chǔ)。其高度特異性和生物活性使其成為免疫學(xué)、分子生物學(xué)及藥理學(xué)等領(lǐng)域研究的理想選擇，支持從基礎(chǔ)機(jī)制研究到藥物候選分子篩選的多樣化科研需求。

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TNFSF

Tumour necrosis factor receptor antagonist(Sorrento Therapeutics) research-grade biosimilar

Human

Recombinant Human TNFSF protein

Homo sapiens (Human)

Non-conjugated

Monoclonal

It differs from different batches. Please contact us to confirm it.

0.01M PBS，pH7.4

Liquid

Validation Status
Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
Guaranteed Quality
① Antibody purity?> 95% tested by SDS-PAGE.
② Endotoxin level < 0.1EU/ug tested by LAL method.

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

3-4 weeks

It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.