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  4. SLC39A12 (APL-9796 Biosimilar) Recombinant Monoclonal Antibody

SLC39A12 (APL-9796 Biosimilar) Recombinant Monoclonal Antibody

  • 貨號(hào)：
    CSB-RA706511MB1HU
  • 規(guī)格：
    ￥83486
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    SLC39A12（APL-9796 Biosimilar Antibody)重組單克隆抗體是一種用于科研領(lǐng)域的生物制劑。該抗體通過基因工程技術(shù)制備，具有高度的特異性和均一性，可作為研究工具用于相關(guān)生物學(xué)機(jī)制的探索。 作為重組單克隆抗體，其生產(chǎn)過程采用先進(jìn)的細(xì)胞培養(yǎng)和蛋白純化技術(shù)，確保產(chǎn)物的高純度和批次間的穩(wěn)定性。這種特性使其在實(shí)驗(yàn)室研究中能夠提供可靠的實(shí)驗(yàn)結(jié)果，支持科研人員開展精準(zhǔn)的生物學(xué)實(shí)驗(yàn)。 在科研應(yīng)用方面，該抗體可用于蛋白質(zhì)檢測(cè)、定位及功能研究等多個(gè)領(lǐng)域。例如，在細(xì)胞生物學(xué)實(shí)驗(yàn)中，可通過等技術(shù)，幫助研究人員觀察SLC39A12蛋白在細(xì)胞內(nèi)的表達(dá)水平和亞細(xì)胞定位，進(jìn)而深入探究其在生理和病理過程中的作用機(jī)制。 此外，該抗體的高度特異性使其能夠特異性識(shí)別靶標(biāo)蛋白，減少非特異性結(jié)合對(duì)實(shí)驗(yàn)結(jié)果的干擾，為科研工作提供有力的技術(shù)支持。其在科研領(lǐng)域的應(yīng)用，有助于推動(dòng)相關(guān)疾病機(jī)制的研究以及潛在治療靶點(diǎn)的發(fā)現(xiàn)，為生命科學(xué)研究做出貢獻(xiàn)。
  • Uniprot No.：
  • 基因名：
  • 別名：
    AP13 research-grade biosimilar; APL9796 research-grade biosimilar; APL 9796 research-grade biosimilar; humanized monoclonal antibody directed against human zinc-regulated transporter-like, iron-regulated transporter-like protein 12 research-grade biosimilar ;SLC39A12 antibody; ZIP12 antibody; Zinc transporter ZIP12 antibody; LIV-1 subfamily of ZIP zinc transporter 8 antibody; LZT-Hs8 antibody; Solute carrier family 39 member 12 antibody; Zrt- and Irt-like protein 12 antibody; ZIP-12 antibody
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human SLC39A12 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    0.01M PBS，pH7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用說明：
    Validation Status
    Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
    Guaranteed Quality
    ① Antibody purity?> 95% tested by SDS-PAGE.
    ② Endotoxin level < 0.1EU/ug tested by LAL method.
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    3-4 weeks
  • 用途：
    It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Acts as a zinc-influx transporter (Potential). May be partly involved in the outbreak of schizophrenia.
  • 基因功能參考文獻(xiàn)：
    1. Data indicate that the zinc transporter ZIP12 (slc39a12) is highly expressed in brain. PMID: 23716681
    2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    3. Examination of the zinc transporter gene, SLC39A12. PMID: 16311021
    4. Observational study of gene-disease association. (HuGE Navigator) PMID: 16385451
    5. Observational study of gene-disease association. (HuGE Navigator) PMID: 19064571

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  • 亞細(xì)胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    ZIP transporter (TC 2.A.5) family
  • 組織特異性：
    Expressed in brain and eye.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 20860

    OMIM: 608734

    KEGG: hsa:221074

    STRING: 9606.ENSP00000366586

    UniGene: Hs.350895



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