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  4. PLD4 (SBI-3150 Biosimilar) Recombinant Monoclonal Antibody

PLD4 (SBI-3150 Biosimilar) Recombinant Monoclonal Antibody

  • 貨號(hào)：
    CSB-RA839298MB1HU
  • 規(guī)格：
    ￥83486
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    PLD4 (SBI-3150 Biosimilar Antibody)重組單克隆抗體是一款專為科研用途開發(fā)的生物試劑，旨在為生命科學(xué)研究提供高質(zhì)量的分子工具。該產(chǎn)品通過基因工程技術(shù)制備，具有高特異性和批次穩(wěn)定性，適用于多種實(shí)驗(yàn)場(chǎng)景。 作為重組單克隆抗體，PLD4 (SBI-3150) 采用先進(jìn)的CHO細(xì)胞表達(dá)系統(tǒng)生產(chǎn)，經(jīng)過嚴(yán)格的純化工藝，確保極低的內(nèi)毒素水平和高純度。其靶向PLD4蛋白的特異性結(jié)合能力，為研究該蛋白在生理和病理過程中的功能提供了可靠支持，可應(yīng)用于等常見分子生物學(xué)實(shí)驗(yàn)。 該抗體在研發(fā)過程中經(jīng)過多輪篩選和驗(yàn)證，確保與靶標(biāo)蛋白的高親和力和低交叉反應(yīng)性。其穩(wěn)定的理化性質(zhì)使其在長期儲(chǔ)存和多次凍融循環(huán)后仍能保持活性，滿足科研實(shí)驗(yàn)對(duì)試劑穩(wěn)定性的嚴(yán)格要求。此外，產(chǎn)品提供詳細(xì)的質(zhì)量控制報(bào)告，包括效價(jià)、純度和活性檢測(cè)數(shù)據(jù)，為實(shí)驗(yàn)結(jié)果的可重復(fù)性和可靠性提供保障。 PLD4 (SBI-3150 Biosimilar Antibody)重組單克隆抗體的應(yīng)用范圍涵蓋基礎(chǔ)醫(yī)學(xué)研究、蛋白質(zhì)功能分析、信號(hào)通路探索等領(lǐng)域，為科研人員深入理解PLD4相關(guān)的分子機(jī)制和疾病模型研究提供有力支持。其標(biāo)準(zhǔn)化的生產(chǎn)流程和嚴(yán)格的質(zhì)量控制體系，使其成為生命科學(xué)研究中值得信賴的實(shí)驗(yàn)工具。
  • Uniprot No.：
  • 基因名：
  • 別名：
    AK1910 research-grade biosimilar; AK 1910 research-grade biosimilar; SBI3150 research-grade biosimilar; SBI 3150 research-grade biosimilar ;PLD4 antibody; C14orf175 antibody; UNQ2488/PRO5775 antibody; 5'-3' exonuclease PLD4 antibody; EC 3.1.16.1 antibody; (S,S-bis(monoacylglycerophosphate synthase PLD4 antibody; EC 3.1.4.- antibody; Phospholipase D family member 4 antibody; Phospholipase D4 antibody
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human PLD4 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    0.01M PBS，pH7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用說明：
    Validation Status
    Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
    Guaranteed Quality
    ① Antibody purity?> 95% tested by SDS-PAGE.
    ② Endotoxin level < 0.1EU/ug tested by LAL method.
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    3-4 weeks
  • 用途：
    It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor. Involved in phagocytosis of activated microglia.
  • 基因功能參考文獻(xiàn)：
    1. PLD4 expression in colon cancer tissues PMID: 27840999
    2. We determined that PLD4 is a novel susceptibility gene for sysetmic sclerosis in Japanese, thus confirming the involvement of PLD4 in autoimmunity. PMID: 23124809
  • 亞細(xì)胞定位：
    Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type II membrane protein. Nucleus. Early endosome. Cytoplasmic vesicle, phagosome.
  • 蛋白家族：
    Phospholipase D family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 23792

    KEGG: hsa:122618

    STRING: 9606.ENSP00000376372

    UniGene: Hs.407101



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