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  4. EGFR&LGR5 (Petosemtamab Biosimilar) Recombinant Monoclonal Antibody

EGFR&LGR5 (Petosemtamab Biosimilar) Recombinant Monoclonal Antibody

  • 貨號：
    CSB-RA012906MB1HU
  • 規(guī)格：
    ￥83486
  • 其他：

產品詳情

  • 產品描述：
    LGR5 (Petosemtamab Biosimilar Antibody) 重組單克隆抗體是一種靶向人源LGR5蛋白，其別名包括FEX抗體、GPR49抗體、GPR67抗體、HG38抗體等，對應靶點為富含亮氨酸重復序列G蛋白偶聯(lián)受體5（LGR5）。該抗體以重組人LGR5蛋白制備，具有高度的種屬特異性，僅對人源LGR5產生免疫反應，為相關研究提供了精準的靶向工具。 Petosemtamab Biosimilar Antibody作為靶向LGR5抗體，Petosemtamab類似物，被探索用于腫瘤靶向治療，通過特異性結合LGR5陽性腫瘤細胞，發(fā)揮抑制腫瘤生長或介導免疫殺傷的作用。目前，其其的研發(fā)聚焦于提高藥物可及性，為患者提供更經(jīng)濟的治療選擇，相關臨床試驗正評估其在實體瘤治療中的安全性和有效性。 該抗體廣泛用于LGR5蛋白的檢測與功能研究，支持實驗。研究人員借助它識別LGR5陽性干細胞群體，探索干細胞在組織再生、腫瘤微環(huán)境中的作用機制，同時為LGR5靶向藥物的篩選和療效評價提供基礎實驗數(shù)據(jù)。其高特異性和種屬反應性確保了實驗結果的可靠性，推動干細胞生物學與腫瘤學領域的機制研究。
  • Uniprot No.：
  • 基因名：
    EGFR&LGR5
  • 別名：
    FEX antibody; G protein coupled receptor 49 antibody; G protein coupled receptor 67 antibody; g protein-coupled receptor fex antibody; G-protein coupled receptor 49 antibody; G-protein coupled receptor 67 antibody; G-protein coupled receptor HG38 antibody; GPCR GPR49 antibody; GPR 49 antibody; GPR 67 antibody; GPR49 antibody; GPR67 antibody; GRP 49 antibody; GRP49 antibody; HG 38 antibody; HG38 antibody; Leucine rich repeat containing G protein coupled receptor 5 antibody; Leucine-rich repeat-containing G-protein coupled receptor 5 antibody; LGR 5 antibody; LGR5 antibody; LGR5_HUMAN antibody; MGC117008 antibody; Orphan G protein coupled receptor HG38 antibody
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human EGFR&LGR5 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    0.01M PBS，pH7.4
  • 產品提供形式：
    Liquid
  • 應用說明：
    Validation Status Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems. Guaranteed Quality ① Antibody purity?> 95% tested by SDS-PAGE. ② Endotoxin level < 0.1EU/ug tested by LAL method.
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    In stock
  • 用途：
    It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.

產品評價



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