KAAG1（CN 103492418 A Biosimilar Antibody）重組單克隆抗體是一種針對腎臟相關(guān)抗原1（Kidney-associated antigen 1），其別名還包括RU2 antisense gene protein和RU2AS。該抗體以重組人KAAG1蛋白制備而成，具有高度的人源種屬反應(yīng)性，專門針對人類KAAG1靶點發(fā)揮作用。 針對KAAG1靶點類似物可能在腎臟疾病的診斷和治療中具有潛在價值。目前針對該靶點的研究主要集中在探索其在腎臟疾病發(fā)生發(fā)展中的作用機制，以及評估相關(guān)藥物的安全性和有效性。由于其其的特性，該抗體研發(fā)的藥物可能為現(xiàn)有治療方案提供更多選擇，尤其在降低治療成本和提高藥物可及性方面具有優(yōu)勢，但具體的臨床應(yīng)用仍需進(jìn)一步的臨床試驗數(shù)據(jù)支持。 KAAG1重組單克隆抗體是研究KAAG1蛋白功能及相關(guān)信號通路的重要工具。研究人員可利用該抗體進(jìn)行實驗，以檢測KAAG1在不同組織和細(xì)胞中的表達(dá)水平與定位，深入探究其在腎臟生理及病理過程中的分子機制。此外，由于其明確的種屬反應(yīng)性，該抗體適用于人類細(xì)胞和組織樣本的研究，為腎臟疾病的基礎(chǔ)研究提供了可靠的試劑支持，有助于推動相關(guān)疾病的診斷標(biāo)志物和治療靶點的發(fā)現(xiàn)。

Q9UBP8

Kidney-associated antigen 1, RU2 antisense gene protein, KAAG1, RU2AS

Human

Recombinant Human KAAG1 protein

Homo sapiens (Human)

Non-conjugated

Monoclonal

It differs from different batches. Please contact us to confirm it.

0.01M PBS，pH7.4

Liquid

Validation Status
Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
Guaranteed Quality
① Antibody purity?> 95% tested by SDS-PAGE.
② Endotoxin level < 0.1EU/ug tested by LAL method.

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

In stock

It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.