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ITPRIPL1 (CN113416253A Biosimilar) Recombinant Monoclonal Antibody

  • 貨號:
    CSB-RA756966MB1HU
  • 規(guī)格:
    ¥83486
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品描述:
    ITPRIPL1(CN113416253A Biosimilar Antibody)重組單克隆抗體是一種針對Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1(簡稱ITPRIPL1,別名KIAA1754L)。該抗體以重組人ITPRIPL1蛋白制備,具有明確的抗原特異性,可精準(zhǔn)識別目標(biāo)蛋白。其種屬反應(yīng)性覆蓋人類和食蟹猴(Macaca fascicularis),為跨物種研究提供了可靠工具。 以ITPRIPL1為靶點(diǎn),CN113416253A類似物開發(fā)為相關(guān)疾病的治療帶來新方向。通過特異性結(jié)合ITPRIPL1蛋白,此類藥物可能參與調(diào)控細(xì)胞內(nèi)鈣信號通路、細(xì)胞增殖或凋亡等生理過程,為探索神經(jīng)系統(tǒng)疾病、腫瘤等疾病的發(fā)病機(jī)制提供實(shí)驗(yàn)依據(jù)。目前,針對該靶點(diǎn)藥物的臨床前研究正逐步推進(jìn),重點(diǎn)評估其藥代動力學(xué)特性、安全性及潛在治療效果。 ITPRIPL1抗體憑借高特異性和種屬交叉反應(yīng)性,廣泛用于蛋白質(zhì)定位、表達(dá)水平檢測及功能分析。研究者可通過技術(shù),在人類和食蟹猴的細(xì)胞或組織樣本中精準(zhǔn)檢測ITPRIPL1的表達(dá)與分布,助力解析該蛋白在生理與病理狀態(tài)下的作用機(jī)制。此外,該抗體也為構(gòu)建疾病動物模型、篩選藥物候選分子等研究提供了關(guān)鍵工具,推動相關(guān)領(lǐng)域的基礎(chǔ)與轉(zhuǎn)化醫(yī)學(xué)研究進(jìn)展。
  • Uniprot No.:
  • 基因名:
  • 別名:
    Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 antibody, ITPRIPL1 antibody, KIAA1754L antibody
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human ITPRIPL1 protein
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 克隆類型:
    Monoclonal
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    0.01M PBS,pH7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用說明:
    Validation Status
    Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
    Guaranteed Quality
    ① Antibody purity?> 95% tested by SDS-PAGE.
    ② Endotoxin level < 0.1EU/ug tested by LAL method.
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    In stock
  • 用途:
    It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.

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