GPR20 (US10906974 Biosimilar Antibody) 重組單克隆抗體是一種針對(duì)G蛋白偶聯(lián)受體20（GPR20），其別名為G protein coupled receptor 20 antibody、G-protein coupled receptor 20 antibody、Gpr20 antibody或GPR20_HUMAN antibody。該抗體以重組人GPR20蛋白制備，具有高度特異性，可與人類及食蟹猴（Macaca fascicularis）的GPR20蛋白發(fā)生特異性結(jié)合，為相關(guān)研究提供了可靠的檢測(cè)工具。 在藥物研發(fā)領(lǐng)域，以 G 蛋白偶聯(lián)受體 GPR20 為靶點(diǎn)的配體、拮抗劑或激動(dòng)劑，有望用于治療因 GPR20 異常表達(dá)或激活引發(fā)的相關(guān)疾病。GPR20 在多種生理和病理過程中發(fā)揮作用，其功能異常與部分神經(jīng)系統(tǒng)疾病、代謝性疾病及腫瘤的發(fā)生發(fā)展密切相關(guān)。這類靶向藥物可通過特異性調(diào)節(jié) GPR20 的活性，達(dá)到改善疾病癥狀、延緩病情進(jìn)展的效果，為相關(guān)疾病的治療方案優(yōu)化提供潛在方向。目前，針對(duì) GPR20 的靶向藥物多處于臨床前或早期臨床試驗(yàn)階段，尚未獲批臨床應(yīng)用。 GPR20重組單克隆抗體可廣泛應(yīng)用于分子生物學(xué)、細(xì)胞生物學(xué)等研究領(lǐng)域。例如，在實(shí)驗(yàn)中，該抗體能夠特異性檢測(cè)GPR20蛋白的表達(dá)水平和亞細(xì)胞定位，助力研究人員揭示GPR20在細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)、組織發(fā)育及疾病模型中的功能。其對(duì)人類和食蟹猴的種屬反應(yīng)性，也為跨物種研究提供了便利，有助于更全面地理解GPR20的生物學(xué)功能及其在不同物種間的保守性與差異性。

Q99678

G protein coupled receptor 20 antibody; G-protein coupled receptor 20 antibody; Gpr20 antibody; GPR20_HUMAN antibody

Human

Recombinant Human GPR20 protein

Homo sapiens (Human)

Non-conjugated

Monoclonal

It differs from different batches. Please contact us to confirm it.

0.01M PBS，pH7.4

Liquid

Validation Status
Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
Guaranteed Quality
① Antibody purity?> 95% tested by SDS-PAGE.
② Endotoxin level < 0.1EU/ug tested by LAL method.

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

In stock

It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.