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  4. BTN1A1 (Nelmastobart Biosimilar) Recombinant Monoclonal Antibody

BTN1A1 (Nelmastobart Biosimilar) Recombinant Monoclonal Antibody

  • 貨號(hào)：
    CSB-RA615684MB1HU
  • 規(guī)格：
    ￥83486
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    BTN1A1(Nelmastobart Biosimilar Antibody)重組單克隆抗體是一種基于重組DNA技術(shù)制備的單克隆抗體，主要用于科研領(lǐng)域的生物學(xué)研究。該抗體通過(guò)特異性識(shí)別和結(jié)合BTN1A1蛋白，為研究其在生理和病理過(guò)程中的功能提供重要工具。 BTN1A1蛋白屬于B7家族成員，在免疫調(diào)節(jié)、細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)等生物學(xué)過(guò)程中發(fā)揮關(guān)鍵作用。本抗體采用基因工程手段，在哺乳動(dòng)物細(xì)胞表達(dá)系統(tǒng)中高效生產(chǎn)，具有高純度、高特異性和良好的批次一致性。其制備過(guò)程嚴(yán)格遵循重組蛋白生產(chǎn)的標(biāo)準(zhǔn)流程，包括目的基因克隆、表達(dá)載體構(gòu)建、細(xì)胞轉(zhuǎn)染、抗體純化及質(zhì)量控制等環(huán)節(jié)，確保產(chǎn)品符合科研實(shí)驗(yàn)的嚴(yán)格要求。 在應(yīng)用方面，BTN1A1重組單克隆抗體可廣泛用于多種實(shí)驗(yàn)方法，助力研究人員深入探究BTN1A1蛋白的表達(dá)模式、亞細(xì)胞定位及其與其他蛋白質(zhì)的相互作用。通過(guò)特異性阻斷或檢測(cè)BTN1A1蛋白，為揭示其在免疫應(yīng)答、疾病發(fā)生發(fā)展等過(guò)程中的分子機(jī)制提供有力支持。 該產(chǎn)品僅用于實(shí)驗(yàn)室研究，不用于臨床診斷或治療。使用時(shí)應(yīng)按照標(biāo)準(zhǔn)實(shí)驗(yàn)操作規(guī)程進(jìn)行，避免交叉污染，確保實(shí)驗(yàn)結(jié)果的準(zhǔn)確性和可重復(fù)性。其穩(wěn)定的理化性質(zhì)和明確的靶向性，使其成為生命科學(xué)研究領(lǐng)域中探索BTN1A1相關(guān)生物學(xué)功能的理想工具。
  • Uniprot No.：
  • 基因名：
  • 別名：
    Anti-butyrophilin 1A1 mAb(STCube/MD Anderson Cancer Center) research-grade biosimilar; Anti STT-003 Ab research-grade biosimilar; HSTC810 research-grade biosimilar; HSTC 810 research-grade biosimilar; STT 003 research-grade biosimilar ;BTN1A1 antibody; BTN antibody; Butyrophilin subfamily 1 member A1 antibody; BT antibody
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human BTN1A1 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類(lèi)型：
    Monoclonal
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    0.01M PBS，pH7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用說(shuō)明：
    Validation Status
    Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
    Guaranteed Quality
    ① Antibody purity?> 95% tested by SDS-PAGE.
    ② Endotoxin level < 0.1EU/ug tested by LAL method.
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    3-4 weeks
  • 用途：
    It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
  • 基因功能參考文獻(xiàn)：
    1. Data illustrated the importance of Akt1 in mammary epithelial cell proliferation, as well as in the regulation of Btn1a1 and subsequent expression of ss-casein. PMID: 21915327
    2. PRY/SPRY/B30.2 domain of butyrophilin 1A1 (BTN1A1) binds to xanthine oxidoreductase PMID: 19531472
  • 亞細(xì)胞定位：
    Membrane; Single-pass type I membrane protein. Secreted.
  • 蛋白家族：
    Immunoglobulin superfamily, BTN/MOG family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 1135

    OMIM: 601610

    KEGG: hsa:696

    STRING: 9606.ENSP00000244513

    UniGene: Hs.153058



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