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  4. Recombinant Human Membrane transport protein XK (XK), partial

Recombinant Human Membrane transport protein XK (XK), partial

  • 中文名稱：
    人XK重組蛋白
  • 貨號：
    CSB-YP026198HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人XK重組蛋白
  • 貨號：
    CSB-EP026198HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人XK重組蛋白
  • 貨號：
    CSB-EP026198HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人XK重組蛋白
  • 貨號：
    CSB-BP026198HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人XK重組蛋白
  • 貨號：
    CSB-MP026198HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    XK
  • Uniprot No.：
  • 別名：
    XK; XKR1; XRG1; Membrane transport protein XK; Kell complex 37 kDa component; Kx antigen; XK-related protein 1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    May be involved in sodium-dependent transport of neutral amino acids or oligopeptides.
  • 基因功能參考文獻：
    1. the expression of KX is critical to normal morphology, and null mutations are associated with the McLeod neuroacanthocytosis syndrome. PMID: 26308465
    2. The XK gene was not linked to hypermutability in red cells from patients with paroxysmal nocturnal hemoglobinuria. PMID: 24816235
    3. study reports the clinical findings and a novel nonsense hemizygous mutation, c.154C>T (p.Gln52X) at exon 1 of XK gene in a Taiwanese family with McLeod syndrome PMID: 24635891
    4. Novel XK protein mutations are reported in two patients who exhibit typical clinical characteristics of McLeod syndrome. PMID: 21463873
    5. This study identified one non-synonymous and one intron variant in mood disorder and schizophrenia subjects, respectively, in XK. PMID: 21145924
    6. In human cortex, the results show expression of XK in cortical neurons with an apparent cytoplasmic localization. PMID: 17379193
    7. Sequence analysis demonstrated a 5 bp deletion in exon 2 of the XK gene in McLeod syndrome. PMID: 17469188

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  • 相關(guān)疾?。?/div>
    McLeod syndrome (MLS)
  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    XK family
  • 組織特異性：
    High levels in skeletal muscle, heart, brain, and pancreas; low levels in placenta, lung, liver, and kidney.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 12811

    OMIM: 300842

    KEGG: hsa:7504

    STRING: 9606.ENSP00000367879

    UniGene: Hs.78919



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