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  4. TAF1C Recombinant Monoclonal Antibody

TAF1C Recombinant Monoclonal Antibody

  • 中文名稱：
    TAF1C Recombinant Monoclonal Antibody
  • 貨號(hào)：
    CSB-RA153039A0HU
  • 規(guī)格：
    ￥1320
  • 圖片：
    • Western blotting analysis using TAF1C antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with TAF1C antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    TAF1C
  • 別名：
    TAF1C; TATA-Box Binding Protein Associated Factor, RNA Polymerase I Subunit C; TAFI110; MGC:39976; TAFI95; SL1; TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa; TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kD; TATA Box-Binding Protein-Associated Factor RNA Polymerase I Subunit C; RNA Polymerase I-Specific TBP-Associated Factor 110 KDa; Transcription Initiation Factor SL1/TIF-IB Subunit C; TATA Box-Binding Protein-Associated Factor 1C; TBP-Associated Factor 1C; TATA-Box Binding Protein Associated Factor, RNA Polymerase I, C; Transcription Factor SL1; SL1, 110kD Subunit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human TAF1C protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號(hào)：
    23B2
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.
  • 基因功能參考文獻(xiàn)：
    1. Our results indicate that TAF1C gene harboured not only somatic frameshift mutations but also the mutational ITH, which together might play a role in tumourigenesis of gastric and colorectal cancer. PMID: 25551296
    2. PTEN represses RNA Pol I transcription through a novel mechanism that involves disruption of the SL1 complex PMID: 16055704
  • 亞細(xì)胞定位：
    Nucleus.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 11534

    OMIM: 604905

    KEGG: hsa:9013

    STRING: 9606.ENSP00000367802

    UniGene: Hs.153022



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