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PWP1 Recombinant Monoclonal Antibody

  • 中文名稱:
    PWP1 Recombinant Monoclonal Antibody
  • 貨號(hào):
    CSB-RA921865A0HU
  • 規(guī)格:
    ¥1320
  • 圖片:
    • Flow cytometric analysis of PWP1 expression in HeLa cells using PWP1 antibody. Green, isotype control; red, PWP1.
    • Immunocytochemical staining of Hela cells with PWP1 antibody. Nuclei were stained blue with DAPI; PWP1 was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 μm.
    • Western blotting analysis using PWP1 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with PWP1 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    PWP1
  • 別名:
    PWP1; PWP1 Homolog, Endonuclein; IEF-SSP-9502; Periodic Tryptophan Protein 1 Homolog; Keratinocyte Protein IEF SSP 9502; Endonuclein; Nuclear Phosphoprotein Similar To S. Cerevisiae PWP1; PWP1 Homolog (S. Cerevisiae); NCLB
  • 反應(yīng)種屬:
    Human, Mouse, Rat
  • 免疫原:
    Recombinant Human PWP1 protein
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 克隆類型:
    Monoclonal
  • 抗體亞型:
    Rabbit IgG
  • 純化方式:
    Affinity-chromatography
  • 克隆號(hào):
    3C12
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, WB, FC, ICC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    FC 1:200-1:2000
    ICC 1:100-1:1000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Chromatin-associated factor that regulates transcription. Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription. Regulates the epigenetic status of rDNA.
  • 基因功能參考文獻(xiàn):
    1. High PWP1 expression is associated with head and neck squamous cell carcinoma. PMID: 29065309
    2. Endonuclein interacts with several proteins indicating a broad function including signal transduction and chaperone activity PMID: 20028516
  • 亞細(xì)胞定位:
    Nucleus. Nucleus, nucleolus. Chromosome.
  • 蛋白家族:
    WD repeat PWP1 family
  • 組織特異性:
    High levels seen in the placenta, skeletal muscle, kidney and pancreas while lower levels were seen in the heart, brain and lung.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 17015

    KEGG: hsa:11137

    STRING: 9606.ENSP00000387365

    UniGene: Hs.506652



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