Flow cytometric analysis of Arginyltransferase 1 expression in HepG2 cells using Arginyltransferase 1 antibody. Green, isotype control; red, Arginyltransferase 1.
Western blotting analysis using arginyltransferase 1 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with arginyltransferase 1 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
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貨期:
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用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues.
基因功能參考文獻:
Ate1 is downregulated in several types of human cancer samples at the protein level, and that its transcription level inversely correlates with metastatic progression and patient survival. PMID: 26686093
Data indicate that arginyltransferase 1 (ATE1) function controls Myocardin-related transcription factor A (MRTF-A) activity. PMID: 25381249