Recombinant Human RNA-binding protein 6 (RBM6), partial

產(chǎn)品詳情

Uniprot No.：

P78332
基因名：

RBM6
別名：

3G2 ; 4930506F14Rik; DEF 3 ; DEF3 ; DKFZp686B0877 ; FLJ36517; g16; HLC 11; KIAA4015; Lung cancer antigen NY LU 12 ; Lung cancer antigen NY-LU-12; Lung cancer protooncogene 11; mKIAA4015; NY LU 12; Protein G16; RBM6; RBM6/RBM5 fusion; RBM6_HUMAN; RGD1560367; RNA binding motif protein 6 ; RNA-binding motif protein 6; RNA-binding protein 6; RNA-binding protein DEF-3
免疫原種屬：

Homo sapiens (Human)
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
應(yīng)用說明：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
儲(chǔ)存條件：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Specifically binds poly(G) RNA homopolymers in vitro.
基因功能參考文獻(xiàn)：
1. Antagonizes the effects of RBM5, RBM6, and RBM10 in cell colony formation. PMID: 24332178
2. identified a novel fusion of the RNA binding motif 6 (RBM6) gene to CSF1R gene generated presumably by a t(3;5)(p21;q33) translocation that induced a myeloid proliferative disease with features of megakaryoblastic leukemia in a murine transplant model PMID: 17360941
3. RBM6 mRNA experiences altered co-transcriptional gene regulation in certain cancers. RBM6-RBM5 transcription-induced chimerism might be a process that is linked to the tumour-associated increased transcriptional activity of the RBM6 gene PMID: 17908320
亞細(xì)胞定位：

Nucleus.
組織特異性：

Ubiquitous in adults.
數(shù)據(jù)庫鏈接：

HGNC: 9903

OMIM: 606886

KEGG: hsa:10180

STRING: 9606.ENSP00000266022

UniGene: Hs.696735