Recombinant Human Nucleolar protein 14 (NOP14), partial

產(chǎn)品詳情

Uniprot No.：

P78316
基因名：

NOP14
別名：

C4orf9; chromosome 4 open reading frame 9; NOL14; NOP 14; NOP14; NOP14 nucleolar protein homolog (yeast); NOP14_HUMAN; Nucleolar complex protein 14; Nucleolar protein 14; Nucleolar protein 14 homolog; RES4 25 ; RES4-25; RES425; UTP2
免疫原種屬：

Homo sapiens (Human)
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
應(yīng)用說明：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
儲存條件：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
基因功能參考文獻(xiàn)：
1. we identified an identical homozygous NOP14 variant as a possible contributing factor for RPL in two Iranian families. PMID: 29440706
2. Targeting NOP14 allows for effective suppression of tumor invasion in a mutp53-dependent manner, implicating NOP14 inhibition as a potential approach for attenuating metastasis in p53-mutant tumors PMID: 28280038
3. our study provides new evidence for NOP14 in regulating PC cell proliferation and migration, and may provide new insights for clinical diagnosis and therapy. PMID: 22425761
亞細(xì)胞定位：

Nucleus, nucleolus.
蛋白家族：

NOP14 family
數(shù)據(jù)庫鏈接：

HGNC: 16821

OMIM: 611526

KEGG: hsa:8602

STRING: 9606.ENSP00000315674

UniGene: Hs.627133