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  4. STARD10 Antibody

STARD10 Antibody

  • 中文名稱：
    STARD10兔多克隆抗體
  • 貨號：
    CSB-PA006725
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of CoLo cells using StARD10 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    STARD10
  • 別名：
    Antigen NY-CO-28 antibody; CGI 52 antibody; MGC14401 antibody; NY CO 28 antibody; PCTL_HUMAN antibody; PCTP-L antibody; PCTP-like protein antibody; PCTP2 antibody; SDCCAG28 antibody; Serologically defined colon cancer antigen 28 antibody; StAR related lipid transfer (START) domain containing 10 antibody; StAR-related lipid transfer protein 10 antibody; StARD10 antibody; START domain containing 10 antibody; START domain-containing protein 10 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human StARD10.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    May play metabolic roles in sperm maturation or fertilization. Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18:1 or 18:2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes.
  • 基因功能參考文獻：
    1. Hence, we provide a molecular explanation for acquired resistance to DTX that is caused by the miR-638 deficiency and subsequent STARD10 upregulation. In consequence, alteration of miR-638/STARD10 cascade may represent an attractive strategy in future adjuvant therapy along with DTX chemotherapy. PMID: 28412359
    2. StarD10 is required for normal insulin secretion, though its deletion enhances proinsulin processing. PMID: 28132686
    3. A nonpredicted link between SNAI1-triggered EMT and the down-regulation of Nectin-1 and StarD10 through the up-regulation of miR-661, which may contribute to the invasion of breast cancer cells and poor disease outcome. PMID: 20543867
    4. Data show that in multivariate analyses incorporating tumor size, tumor grade, lymph node status, ER, PR and HER2 status, low STARD10 expression was an independent predictor of death from breast cancer. PMID: 19676041
    5. StarD10 interacts with phosphatidylcholine and phosphatidylethanolamine and preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18:1 or 18:2) on the sn-2 position PMID: 15911624
    6. C-terminal StarD10 phosphorylation on serine 284 regulates its association with cellular membranes PMID: 17561512
    7. Stard10 (Sdccag28) is much more highly transcribed in mouse cardiac atria than in cardiac ventricles. PMID: 14576202

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  • 亞細胞定位：
    Cell projection, cilium, flagellum. Cytoplasm. Membrane.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 10666

    OMIM: 617382

    KEGG: hsa:10809

    STRING: 9606.ENSP00000335247

    UniGene: Hs.188606



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