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  4. SLC16A10 Antibody, FITC conjugated

SLC16A10 Antibody, FITC conjugated

  • 中文名稱：
    SLC16A10兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA851563HC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SLC16A10 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SLC16A10
  • 別名：
    SLC16A10 antibody; MCT10 antibody; TAT1 antibody; Monocarboxylate transporter 10 antibody; MCT 10 antibody; Aromatic amino acid transporter 1 antibody; Solute carrier family 16 member 10 antibody; T-type amino acid transporter 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Monocarboxylate transporter 10 protein (159-201AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Sodium-independent transporter that mediates the uptake of aromatic acids. Can function as a net efflux pathway for aromatic amino acids in the basosolateral epithelial cells.
  • 基因功能參考文獻：
    1. In the MCT10 modeled structure, N81 appeared to protrude into the putative trajectory of tryptophan. PMID: 28754537
    2. the aim of this study was to examine if MCT8 and MCT10 increase the availability of triiodothyronine for its nuclear receptor. PMID: 27492966
    3. High TAT1 expression is associated with metastasis and recurrence in endometrial cancer. PMID: 26779635
    4. monocarboxylate transporter 10 facilitates bromoacetyl [(125)I] iodothyronine transport, but is not labeled by it PMID: 21315799
    5. Increased MCT8 and decreased MCT10 expression within placentae of pregnancies complicated by IUGR may contribute to aberrant development of the fetoplacental unit. PMID: 20167367
    6. MCT10 is at least as active a thyroid hormone transporter as hMCT8, and that both transporters facilitate iodothyronine uptake as well as efflux. PMID: 18337592

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  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein. Basolateral cell membrane.
  • 蛋白家族：
    Major facilitator superfamily, Monocarboxylate porter (TC 2.A.1.13) family
  • 組織特異性：
    Strongly expressed in kidney and skeletal muscle and at lower level in placenta and heart.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17027

    OMIM: 607550

    KEGG: hsa:117247

    STRING: 9606.ENSP00000357844

    UniGene: Hs.591327



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