SF3B6 Antibody

說(shuō)明書(shū)

中文名稱(chēng)：

SF3B6兔多克隆抗體
貨號(hào)：

CSB-PA897543LA01HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA897543LA01HU at dilution of 1:100
其他：

產(chǎn)品詳情

產(chǎn)品名稱(chēng)：

Rabbit anti-Homo sapiens (Human) SF3B6 Polyclonal antibody
Uniprot No.：

Q9Y3B4
基因名：

SF3B6
別名：

Ht006 antibody; P14 antibody; PM14_HUMAN antibody; Pre mRNA branch site protein p14 antibody; Pre-mRNA branch site protein p14 antibody; SAP14 antibody; SF3B 14 kDa subunit antibody; SF3B14 antibody; SF3B14a antibody; Splicing factor 3B, 14 kDa subunit antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Splicing factor 3B subunit 6 protein (1-125AA)
免疫原種屬：

Homo sapiens (Human)

標(biāo)記方式：

Non-conjugated

本頁(yè)面中的產(chǎn)品，SF3B6 Antibody (CSB-PA897543LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于SF3B6 Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

標(biāo)記方式	貨號(hào)	產(chǎn)品名稱(chēng)	應(yīng)用
HRP	CSB-PA897543LB01HU	SF3B6 Antibody, HRP conjugated	ELISA
FITC	CSB-PA897543LC01HU	SF3B6 Antibody, FITC conjugated
Biotin	CSB-PA897543LD01HU	SF3B6 Antibody, Biotin conjugated	ELISA

克隆類(lèi)型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing. Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively.
基因功能參考文獻(xiàn)：
1. the p14-RNA interaction screens charges on the backbone of the branch site during spliceosome assembly. PMID: 26784522
2. determined the high resolution structure of a complex between SF3b14 and a peptide derived from SF3b155 and proposed a model for recognition of the pre-mRNA branch sequence adenosine. PMID: 16432215
亞細(xì)胞定位：

Nucleus.
蛋白家族：

SF3B6 family
數(shù)據(jù)庫(kù)鏈接：

HGNC: 30096

OMIM: 607835

KEGG: hsa:51639

STRING: 9606.ENSP00000233468

UniGene: Hs.177861