SERPINB8 Antibody

產(chǎn)品詳情

Uniprot No.：

P50452
基因名：

SERPINB8
別名：

CAP 2 antibody; CAP-2 antibody; CAP2 antibody; Cytoplasmic antiproteinase 2 antibody; OTTHUMP00000067000 antibody; OTTHUMP00000067001 antibody; Peptidase inhibitor 8 antibody; PI 8 antibody; PI-8 antibody; PI8 antibody; Protease inhibitor 8 (ovalbumin type) antibody; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 8 antibody; Serpin B8 antibody; Serpin peptidase inhibitor clade B (ovalbumin) member 8 antibody; Serpinb8 antibody; SPB8_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human SERPINB8
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Has an important role in epithelial desmosome-mediated cell-cell adhesion.
基因功能參考文獻：
1. report of mutations in SERPINB8 that are associated with exfoliative ichthyosis and provide evidence that SERPINB8 contributes to the mechanical stability of intercellular adhesions in the epidermis PMID: 27476651
2. PI8 is released by platelets and controls functional responses PMID: 16493485
3. Data show that SERPINB8 is expressed in normal neuroendocrine cells of several organs as well as in neuroendocrine tumors of the pancreas, where it can be used as an additional diagnostic immunohistochemical marker. PMID: 19188865
相關疾病：

Peeling skin syndrome 5 (PSS5)
亞細胞定位：

Cytoplasm.
蛋白家族：

Serpin family, Ov-serpin subfamily
數(shù)據(jù)庫鏈接：

HGNC: 8952

OMIM: 601697

KEGG: hsa:5271

STRING: 9606.ENSP00000331368

UniGene: Hs.368077