RTFDC1 Antibody

產(chǎn)品詳情

Uniprot No.：

Q9BY42
基因名：

RTFDC1
別名：

RTF2 antibody; C20orf43 antibody; RTFDC1 antibody; AD-007 antibody; CDA05 antibody; HSPC164 antibody; HSPC169 antibody; Replication termination factor 2 antibody; RTF2 antibody; Replication termination factor 2 domain-containing protein 1 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human C20orf43
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Replication termination factor which is a component of the elongating replisome. Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication. Might function to facilitate fork pausing at replication fork barriers like the rDNA. May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion. Interacts with nascent DNA.
基因功能參考文獻(xiàn)：
1. The results establish that RTF2 removal is a key determinant for the ability of cells to manage replication stress and maintain genome integrity. PMID: 29290612
亞細(xì)胞定位：

Chromosome.
蛋白家族：

Rtf2 family
數(shù)據(jù)庫鏈接：

HGNC: 15890

KEGG: hsa:51507

STRING: 9606.ENSP00000023939

UniGene: Hs.517134