NEMF Antibody

中文名稱：

NEMF兔多克隆抗體
貨號：

CSB-PA003494
規(guī)格：

￥1090
圖片：
Western Blot analysis of 3T3 cells using NY-CO-1 Polyclonal Antibody

Western Blot analysis of NIH-3T3 cells using NY-CO-1 Polyclonal Antibody
其他：

產(chǎn)品詳情

Uniprot No.：

O60524
基因名：

NEMF
別名：

1500011I12Rik antibody; 4933405E14Rik antibody; Antigen NY-CO-1 antibody; FLJ10051 antibody; Nemf antibody; NEMF_HUMAN antibody; Nuclear export mediator factor Nemf antibody; NY CO 1 antibody; SDCCAG1 antibody; SDCG1 antibody; Serologically defined colon cancer antigen 1 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Synthesized peptide derived from the C-terminal region of Human NY-CO-1.
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

WB, IHC, ELISA

推薦稀釋比：

Protocols：

Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. NEMF is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety. NEMF is important for the stable association of LTN1 to the complex. May indirectly play a role in nuclear export.
基因功能參考文獻(xiàn)：
1. Results show that Listerin specificity for nascent chain-60S complexes depends on nuclear export mediator factor. PMID: 25578875
亞細(xì)胞定位：

Nucleus.
蛋白家族：

NEMF family
組織特異性：

Expressed in brain, heart, liver, lung, spleen, and skeletal muscle. Also expressed at lower levels in stomach and testis.
數(shù)據(jù)庫鏈接：

HGNC: 10663

OMIM: 608378

KEGG: hsa:9147

STRING: 9606.ENSP00000298310

UniGene: Hs.655964