MEIKIN Antibody, HRP conjugated

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) MEIKIN Polyclonal antibody
Uniprot No.：

A0A087WXM9
基因名：

MEIKIN
別名：

MEIKINMeiosis-specific kinetochore protein antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Meiosis-specific kinetochore protein (18-91AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Key regulator of kinetochore function during meiosis I: required both for mono-orientation of kinetochores on sister chromosomes and protection of centromeric cohesin from separase-mediated cleavage. Acts by facilitating kinetochore mono-orientation during meiosis I, when kinetochores on sister chromosomes face the same direction and are thus captured and pulled by spindle fibers from the same pole. Also required to prevent cleavage of cohesin at centromeres during meiosis I, possibly by acting as a regulator of the shugoshin-dependent protection pathway. Acts in collaboration with PLK1: required for PLK1 enrichment to kinetochores. Not required during meiosis II or mitosis.
基因功能參考文獻：
1. Single marker analysis indicated that SNP5 (rs1355095) in LOC728637 is associated with schizophrenia in Han Chinese. PMID: 18718982
亞細胞定位：

Chromosome, centromere. Chromosome, centromere, kinetochore.
數(shù)據(jù)庫鏈接：

HGNC: 51253

OMIM: 616223

KEGG: hsa:728637

UniGene: Hs.631802