LACTB2 Antibody

說(shuō)明書

產(chǎn)品詳情

Uniprot No.：

Q53H82
基因名：

LACTB2
別名：

Beta lactamase like protein 2 antibody; Beta-lactamase-like protein 2 antibody; CGI 83 antibody; CGI-83 antibody; LACB2_HUMAN antibody; Lactamase beta 2 antibody; LACTB2 antibody; MGC112672 antibody; MGC140671 antibody; MGC7674 antibody; OTTHUMP00000226691 antibody; OTTHUMP00000226692 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human LACTB2
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB,IHC,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.
基因功能參考文獻(xiàn)：
1. This genome-wide study of never smokers from the general population identified two independent regions related to erythrocyte cadmium. The strongest locus covers the XKR9 and LACTB2 genes, which both could have related functions in cadmium absorption and metabolism PMID: 27005419
2. this study discovered that LACTB2 is an endoribonuclease that is involved in the turnover of mitochondrial RNA, and is essential for mitochondrial function in human cells. PMID: 26826708
3. Disruption of NCOA2 by recurrent fusion with LACTB2 in colorectal cancer PMID: 25823027
亞細(xì)胞定位：

Mitochondrion matrix.
蛋白家族：

Metallo-beta-lactamase superfamily, Glyoxalase II family
數(shù)據(jù)庫(kù)鏈接：

HGNC: 18512

KEGG: hsa:51110

STRING: 9606.ENSP00000276590

UniGene: Hs.118554