KIAA0100 Antibody

說(shuō)明書(shū)

產(chǎn)品詳情

Uniprot No.：

Q14667
基因名：

KIAA0100
別名：

Antigen MLAA-22 antibody; BCOX antibody; BCOX1 antibody; Breast cancer-overexpressed gene 1 protein antibody; CT101 antibody; DKFZp686M0843 antibody; K0100_HUMAN antibody; KIAA0100 antibody; MGC111488 antibody; MGC134981 antibody; UPF0378 protein KIAA0100 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Synthesized peptide derived from the Internal region of Human KIAA0100.
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

IHC, IF, ELISA

推薦稀釋比：

Protocols：

Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May be involved in membrane trafficking.
基因功能參考文獻(xiàn)：
1. loss of miR-195 expression and thus uncontrolled BCOX1 upregulation might drive prostate cancer metastasis. PMID: 26338045
2. High BCOX1 expression may serve as a novel marker of poor prognosis and a potential therapeutic target for patients with invasive ductal carcinomas of the breast. PMID: 24489812
3. MLAA-22 is a novel acute monocytic leukemia-associated antigen gene located on chromosome 17q11.2. PMID: 18549609
4. BCOX1 mRNA signal is mainly located in the cytoplasm of breast carcinoma epithelial cells. mRNA expression was moderately elevated in ductal in situ carcinoma, peaked in invasive breast carcinoma and metastatic breast carcinoma cells (MET) (BCOX1) PMID: 16289875
亞細(xì)胞定位：

Secreted.
蛋白家族：

SABRE family
組織特異性：

Expressed in pancreas, placenta and up-regulated in breast carcinoma epithelial cells, ductal in situ carcinoma (DCIS), invasive breast carcinoma (IBC) and metastatic breast carcinoma cells (MET).
數(shù)據(jù)庫(kù)鏈接：

HGNC: 28960

OMIM: 610664

KEGG: hsa:9703

UniGene: Hs.151761