Western blot
All lanes: HARS2 antibody at 2µg/ml + Mouse kidney tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 57, 55 kDa
Observed band size: 57 kDa
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA010138HA01HU at dilution of 1:100
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Mitochondrial aminoacyl-tRNA synthetase that catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP).
基因功能參考文獻(xiàn):
Mutations in mitochondrial histidyl tRNA synthetase HARS2 cause ovarian dysgenesis and sensorineural hearing loss of Perrault syndrome. PMID: 21464306
This protein has been found differentially expressed in the anterior cingulate cortex in men patients with schizophrenia. PMID: 20381070
相關(guān)疾病:
Perrault syndrome 2 (PRLTS2)
亞細(xì)胞定位:
Mitochondrion.
蛋白家族:
Class-II aminoacyl-tRNA synthetase family
組織特異性:
A high level expression is seen in the heart, kidney and skeletal muscle while a lower level expression is seen in the brain and liver.