FASTKD1 Antibody

中文名稱：

FASTKD1兔多克隆抗體
貨號：

CSB-PA182654
規(guī)格：

￥1100
圖片：
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA182654(FASTKD1 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)
其他：

產品詳情

Uniprot No.：

Q53R41
基因名：

FASTKD1
別名：

FAKD1_HUMAN antibody; FAST kinase domain containing protein 1 antibody; FAST kinase domain-containing protein 1 antibody; FAST kinase domains 1 antibody; FASTKD1 antibody; FLJ21901 antibody; KIAA1800 antibody; OTTHUMP00000207008 antibody; OTTHUMP00000207010 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Fusion protein of Human FASTKD1
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

Antigen affinity purification
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
產品提供形式：

Liquid
應用范圍：

ELISA,IHC

推薦稀釋比：

Application	Recommended Dilution
ELISA	1:2000-1:10000
IHC	1:100-1:300

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in the down-regulation of mitochondrial MT-ND3 mRNA levels which leads to decreased respiratory complex I abundance and activity.
基因功能參考文獻：
1. Disruption of FASTKD1 increases ND3 mRNA level. Disrupting FASTKD1 and FASTKD4 decreases ND3 mRNA like depleting FASTKD4 alone. Each RAP domain of FASTK proteins contains a nuclease fold with a conserved aspartate residue at the putative active site. The RAP domain is essential for the function of the FASTK proteins, while the region upstream determines RNA targeting and protein localization. PMID: 28335001
亞細胞定位：

Mitochondrion.
蛋白家族：

FAST kinase family
組織特異性：

Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart.
數(shù)據(jù)庫鏈接：

HGNC: 26150

OMIM: 617529

KEGG: hsa:79675

UniGene: Hs.529276