EPSTI1 Antibody, HRP conjugated

說(shuō)明書(shū)

產(chǎn)品詳情

產(chǎn)品名稱(chēng)：

Rabbit anti-Homo sapiens (Human) EPSTI1 Polyclonal antibody
Uniprot No.：

Q96J88
基因名：

EPSTI1
別名：

BRESI 1 antibody; BRESI1 antibody; Epithelial stromal interaction 1 (breast) antibody; Epithelial stromal interaction protein 1 (breast) antibody; Epithelial stromal interaction protein 1 antibody; Epithelial-stromal interaction protein 1 antibody; EPSTI 1 antibody; Epsti1 antibody; ESIP1_HUMAN antibody; MGC29634 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Epithelial-stromal interaction protein 1 protein (12-56AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

HRP
克隆類(lèi)型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation. Might play a role in RELA/p65 and STAT1 phosphorylation and nuclear localization upon activation of macrophages.
基因功能參考文獻(xiàn)：
1. A novel KLF8 to EPSTI1 to VCP to NF-kappaB signaling mechanism potentially critical for breast cancer invasion and metastasis. PMID: 24096480
2. These observations implicate EPSTI1 as a hitherto unappreciated regulator of tumor cell properties. PMID: 20133812
組織特異性：

Highly expressed in placenta, small intestine, spleen, kidney, thymus, liver, salivary gland and testes. Weakly expressed in breast, skeletal muscle and colon. Highly expressed in breast cancer upon interaction between tumor cells and stromal cells in vit
數(shù)據(jù)庫(kù)鏈接：

HGNC: 16465

OMIM: 607441

KEGG: hsa:94240

STRING: 9606.ENSP00000318982

UniGene: Hs.546467