CDC42EP5 Antibody

產(chǎn)品詳情

Uniprot No.：

Q6NZY7
基因名：

CDC42EP5
別名：

CDC42EP5 antibody; BORG3 antibody; CEP5 antibody; Cdc42 effector protein 5 antibody; Binder of Rho GTPases 3 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse
免疫原：

Synthesized peptide derived from the N-terminal region of Human Cdc42EP5.
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

WB, IHC, ELISA

推薦稀釋比：

Protocols：

Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42.
基因功能參考文獻(xiàn)：
1. Studies indicate some of the functional and mechanistic roles of the binder of Rho GTPases Borg1-5 proteins (Cdc42EP1-5), including cytoskeletal remodelling and signalling. PMID: 27913681
亞細(xì)胞定位：

Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.
蛋白家族：

BORG/CEP family
數(shù)據(jù)庫鏈接：

HGNC: 17408

OMIM: 609171

KEGG: hsa:148170

STRING: 9606.ENSP00000301200

UniGene: Hs.415791