BIN2 Antibody

說(shuō)明書

產(chǎn)品詳情

Uniprot No.：

Q9UBW5
基因名：

BIN2
別名：

BIN2 antibody; BRAP1Bridging integrator 2 antibody; Breast cancer-associated protein 1 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Human BIN2
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton. Modulates membrane curvature and mediates membrane tubulation. Plays a role in podosome formation. Inhibits phagocytosis.
基因功能參考文獻(xiàn)：
1. Bin2 is a membrane-sculpting protein that influences podosome formation, motility and phagocytosis in leucocytes. PMID: 23285027
2. Bin2 is a BAR domain adapter protein structurally related but functionally distinct from family members Bin1 and amphiphysin. PMID: 10903846
亞細(xì)胞定位：

Cytoplasm. Cell projection, podosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cell cortex. Cell projection, phagocytic cup.
組織特異性：

Detected in natural killer cells (at protein level). Highest level expression seen in spleen and peripheral blood leukocytes and is also expressed at high levels in thymus, colon and placenta, suggesting preferential expression in hematopoietic tissues.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 1053

OMIM: 605936

KEGG: hsa:51411

STRING: 9606.ENSP00000267012

UniGene: Hs.14770