ADAMTS19 Antibody

說(shuō)明書(shū)

產(chǎn)品詳情

Uniprot No.：

Q8TE59
基因名：

ADAMTS19
別名：

ADAMTS19A disintegrin and metalloproteinase with thrombospondin motifs 19 antibody; ADAM-TS 19 antibody; ADAM-TS19 antibody; ADAMTS-19 antibody; EC 3.4.24.- antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse
免疫原：

Synthesized peptide derived from the Internal region of Human ADAMTS-19.
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:40000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

基因功能參考文獻(xiàn)：
1. The pregnancy loss rate does not appear to be affected by both ADAMTS-13 and ADAMTS-19. PMID: 28088271
2. We found that the AAAAA, AGGAG, and AGGGA haplotypes in ACVR2B were associated with susceptibility to Premature Ovarian Failure when they also had at least one CATAG haplotype in ADAMTS19. PMID: 25051287
3. Synergistic interactions were detected between SNPs, including a non-synonymous SNP, and diplotypes within IGF2R and ADAMTS19 which may contribute to POF. PMID: 24014609
4. Although limited by sample size, this proof-of-principle study's findings reveal ADAMTS19 as a possible candidate gene for premature ovarian failure and thus a larger follow-up study is warranted. PMID: 19508998
亞細(xì)胞定位：

Secreted, extracellular space, extracellular matrix.
組織特異性：

Expressed in fetal lung, but not in any adult tissues examined. Expression was detected in an osteosarcoma cDNA library.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 17111

OMIM: 607513

KEGG: hsa:171019

STRING: 9606.ENSP00000274487

UniGene: Hs.23751