Single-stranded DNA-binding protein Antibody, HRP conjugated

Name: Single-stranded DNA-binding protein Antibody, HRP conjugated
Brand: CUSABIO
SKU: CSB-PA366021HB01EEB

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說明書

產品詳情

產品名稱：

Rabbit anti-Enterobacteria phage T7 2.5 Polyclonal antibody
Uniprot No.：

P03696
基因名：

2.5
別名：

2.5, Single-stranded DNA-binding protein gp2.5 antibody; SSB protein antibody
宿主：

Rabbit
反應種屬：

Enterobacteria phage T7
免疫原：

Recombinant Enterobacteria phage T7 Single-stranded DNA-binding protein gp2.5 protein (1-232AA)
免疫原種屬：

Enterobacteria phage T7
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Single-stranded DNA-binding protein that participates in viral DNA replication, formation of concatemers, recombination and repair of double-stranded breaks. Coats the lagging-strand ssDNA as the replication fork advances and stimulates the activities of viral DNA polymerase and primase/helicase. Coordinates simultaneous synthesis of leading- and lagging-strands. Together with DNA primase/helicase, promotes pairing of two homologous DNA molecules containing complementary single-stranded regions and mediates homologous DNA strand exchange. Promotes also the formation of joint molecules. Disrupts loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation.
基因功能參考文獻：
1. analysis of the interaction of the single-stranded DNA-binding protein of bacteriophage T7 with the DNA polymerase-thioredoxin complex PMID: 20375019
2. results support a model in which dimerization interactions must be broken for DNA binding, and gp2.5 monomers search dsDNA by 1D diffusion to bind ssDNA. PMID: 18772224
數據庫鏈接：

KEGG: vg:1261080