CUSABIO貨號：CSB-MA930245 UCHL1單克隆抗體是一款特異性識別人類泛素羧基末端水解酶L1（UCHL1）的科研用試劑，該靶蛋白作為神經(jīng)元特異性去泛素化酶，在調(diào)控蛋白質(zhì)穩(wěn)態(tài)及神經(jīng)退行性疾病機(jī)制研究中具有重要價(jià)值。本產(chǎn)品采用雜交瘤技術(shù)制備，經(jīng)ELISA、Western Blot（WB）和免疫細(xì)胞化學(xué)（ICC）三大實(shí)驗(yàn)平臺嚴(yán)格驗(yàn)證，展現(xiàn)出優(yōu)異的抗原結(jié)合能力與實(shí)驗(yàn)重復(fù)性，適用于神經(jīng)細(xì)胞蛋白質(zhì)組學(xué)分析、帕金森病相關(guān)α-突觸核蛋白聚集機(jī)制研究以及腦脊液生物標(biāo)志物檢測等科研場景。作為泛素-蛋白酶體系統(tǒng)的關(guān)鍵調(diào)控因子，UCHL1在維持神經(jīng)元功能、調(diào)控細(xì)胞周期及DNA損傷修復(fù)過程中發(fā)揮重要作用，其異常表達(dá)與阿爾茨海默病、膠質(zhì)瘤等病理過程密切相關(guān)。該抗體為科研人員探究神經(jīng)退行性疾病分子機(jī)制、開發(fā)新型研究模型提供可靠工具，滿足蛋白質(zhì)相互作用研究、疾病模型構(gòu)建及藥物靶點(diǎn)篩選等多元化實(shí)驗(yàn)需求。

Neuron cytoplasmic protein 9.5; PGP 9.5; Ubiquitin thioesterase L1

Mouse

Human

Purified recombinant Human UCHL1. protein fragments expressed in E.coli.

Homo sapiens (Human)

Monoclonal

IgG2b

Affinity purified

2H4

It differs from different batches. Please contact us to confirm it.

Purified mouse monoclonal in PBS(pH 7.4) containing with 0.2% sodium azide, 50% glycerol, 0.1%BSA

ELISA,WB,ICC

Application	Recommended Dilution
WB	1:500-1:5000
ICC	1:50-1:200

ELISA Protocol
Western Blotting (WB) Protocol

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.