Pan Methylated Lysine Monoclonal Antibody（CUSABIO貨號(hào)：CSB-MA080224）是一款高特異性科研用抗體，專(zhuān)為檢測(cè)蛋白質(zhì)中賴氨酸位點(diǎn)的甲基化修飾而設(shè)計(jì)。甲基化修飾是表觀遺傳調(diào)控的關(guān)鍵機(jī)制之一，廣泛參與基因表達(dá)調(diào)控、染色質(zhì)重塑及細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)等重要生物學(xué)過(guò)程，在腫瘤發(fā)生、干細(xì)胞分化及神經(jīng)退行性疾病研究中具有重要價(jià)值。該抗體通過(guò)雜交瘤技術(shù)制備，可識(shí)別多種甲基化修飾形式（包括單甲基化、雙甲基化和三甲基化），適用于ELISA、Western Blot及免疫組化（IHC）等實(shí)驗(yàn)方法，其廣譜物種反應(yīng)性支持小鼠、大鼠、人類(lèi)等多種模式生物的樣本檢測(cè)。實(shí)驗(yàn)數(shù)據(jù)顯示其對(duì)甲基化賴氨酸表位具有優(yōu)異結(jié)合能力，在低豐度靶標(biāo)檢測(cè)中仍保持高靈敏度，適用于蛋白質(zhì)翻譯后修飾分析、甲基化相關(guān)信號(hào)通路研究及疾病分子機(jī)制探索等科研場(chǎng)景。該產(chǎn)品嚴(yán)格質(zhì)控批次穩(wěn)定性，為表觀遺傳學(xué)、癌癥生物學(xué)及細(xì)胞代謝研究領(lǐng)域提供可靠工具，助力甲基化動(dòng)態(tài)調(diào)控的功能解析與組學(xué)聯(lián)合研究。

Mouse

All

Conjugated Protein

All

Non-conjugated

IgG

7H8

It differs from different batches. Please contact us to confirm it.

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Liquid

ELISA,WB,IHC

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:50-1:500

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.