JMJD6單克隆抗體（CUSABIO貨號(hào)：CSB-MA184549）是專為檢測(cè)JMJD6靶點(diǎn)設(shè)計(jì)的科研用免疫試劑，靶向Jumonji結(jié)構(gòu)域蛋白家族成員JMJD6。該蛋白作為組蛋白去甲基化酶參與表觀遺傳調(diào)控，在RNA剪接、血管生成及胚胎發(fā)育等生物過(guò)程中發(fā)揮關(guān)鍵作用，其異常表達(dá)與腫瘤發(fā)生及免疫調(diào)控密切相關(guān)。本產(chǎn)品經(jīng)嚴(yán)格驗(yàn)證適用于人、犬、小鼠、大鼠多物種樣本，可在ELISA實(shí)驗(yàn)中實(shí)現(xiàn)精準(zhǔn)定量檢測(cè)，Western Blot技術(shù)中清晰識(shí)別約60-70kDa的靶蛋白條帶，并支持免疫細(xì)胞化學(xué)（ICC）實(shí)驗(yàn)進(jìn)行亞細(xì)胞定位分析。抗體采用高純度重組蛋白免疫制備，具備優(yōu)異的特異性和批次穩(wěn)定性，特別適用于腫瘤微環(huán)境研究、干細(xì)胞分化機(jī)制探索以及表觀遺傳學(xué)相關(guān)的基礎(chǔ)科研項(xiàng)目。實(shí)驗(yàn)方案優(yōu)化顯示其在常規(guī)細(xì)胞裂解液及組織樣本中均表現(xiàn)穩(wěn)定，為研究人員在分子互作研究、信號(hào)通路解析及疾病模型構(gòu)建等方向提供可靠工具。本產(chǎn)品嚴(yán)格遵循科研用途標(biāo)準(zhǔn)，配套提供詳細(xì)實(shí)驗(yàn)條件參考，助力表觀遺傳調(diào)控領(lǐng)域的創(chuàng)新發(fā)現(xiàn)。

bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 lysyl-hydroxylase JMJD6 phosphatidylserine receptor jmjC domain-containing protein 6 histone arginine demethylase JMJD6 peptide-lysine 5-dioxygenase JMJD6 jumonji doma

Mouse

Human,Dog,Mouse,Rat

Recombinant fragment, corresponding to amino acids 11-248aa of Human JMJD6(N-terminus).

Homo sapiens (Human)

Monoclonal

IgG1

Antigen Affinity Purified

5G6

It differs from different batches. Please contact us to confirm it.

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

ELISA,WB,ICC

Application	Recommended Dilution
WB	1:500-1:5000
ICC	1:50-1:200

ELISA Protocol
Western Blotting (WB) Protocol

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.